Document Detail


Pregnancy-induced analgesia: effects of adrenalectomy and glucocorticoid replacement.
MedLine Citation:
PMID:  6093938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During pregnancy, rats show a progressive increase in jump threshold which is followed by a precipitous decrease after delivery. Overall, this pattern of change in pain threshold was not affected by adrenalectomy, with or without corticosterone replacement. It appears, therefore, that the adrenal glands are not necessary for the manifestation of opioid analgesia during pregnancy.
Authors:
S A Baron; A R Gintzler
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Brain research     Volume:  321     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1984 Nov 
Date Detail:
Created Date:  1985-01-24     Completed Date:  1985-01-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  341-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adrenalectomy
Animals
Corticosterone / physiology*
Endorphins / blood
Female
Pain / physiopathology*
Pregnancy
Pregnancy, Animal*
Rats
Rats, Inbred Strains
Sensory Thresholds
Stress, Physiological / physiopathology
beta-Endorphin
Grant Support
ID/Acronym/Agency:
DA 02893/DA/NIDA NIH HHS; HD06488/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Endorphins; 50-22-6/Corticosterone; 60617-12-1/beta-Endorphin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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