Document Detail

Pregnancy in a woman with chronic neutrophilic leukemia.
MedLine Citation:
PMID:  23344408     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: : Chronic neutrophilic leukemia is a rare myeloproliferative disorder in women of reproductive age.
CASE: : A pregnant woman with an established diagnosis of chronic neutrophilic leukemia presented at 26 weeks of gestation with splenomegaly, thrombocytopenia, leukocytosis, and anemia. Thrombocytopenia was refractory to medical treatment and, in part, was attributed to splenic sequestration. She delivered a healthy neonate at 35 weeks of gestation by repeat cesarean delivery under general anesthesia. Her preoperative platelet count was 30,000/mL and she was transfused platelets throughout the perioperative period. Her postpartum course was complicated by intraabdominal hemorrhage and severe preeclampsia. She recovered with intensive medical and surgical management.
CONCLUSION: : Chronic neutrophilic leukemia poses difficult challenges during pregnancy and requires a multidisciplinary approach.
Jolyn Taylor; Gail J Roboz; Rebecca N Baergen; Mehmet R Genc
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  121     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  457-60     Citation Subset:  AIM; IM    
Departments of Obstetrics and Gynecology, Hematology, and Pathology, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York.
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