Document Detail

Pregnancy in postural orthostatic tachycardia syndrome.
MedLine Citation:
PMID:  15955196     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Postural orthostatic tachycardia syndrome (POTS) is a rare disease characterized by syncope, sinus tachycardia, and orthostasis due to autonomic dysfunction. METHODS AND RESULTS: Two women aged 26 and 24 years with severe POTS became pregnant. Both women experienced hyperemesis gravidarum with subsequent marked improvement in their POTS symptoms until 6 months gestation, when their syncope and sinus tachycardia caused clinical decompensation. Both patients delivered healthy babies at 37 weeks by elective cesarean section. CONCLUSION: In long-term follow-up, both women reported improvement in their prepartum symptoms. We describe the first report, to our knowledge, of two successful pregnancy outcomes in severe POTS, including the first report of midodrine use in pregnant women.
Kathryn A Glatter; Dipika Tuteja; Nipavan Chiamvimonvat; Mohamed Hamdan; Jeanny K Park
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  28     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-15     Completed Date:  2006-01-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  591-3     Citation Subset:  IM    
Department of Adult Cardiology, University of California-Davis, 4860 Y Street, Suite 2820, Sacramento, CA 95817, USA.
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MeSH Terms
Dizziness / therapy*
Pregnancy Complications, Cardiovascular / therapy*
Pregnancy Outcome
Syncope / therapy*
Tachycardia / therapy*

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