Document Detail

Pregnancy in patients with systemic lupus erythematosus.
MedLine Citation:
PMID:  10099744     Owner:  NLM     Status:  MEDLINE    
We reviewed the obstetrical performance and outcome of 15 pregnancies in patients with systemic lupus erythematosus (SLE) (study group) and compared them with 45 age and parity-matched normal pregnancies (control group). Eleven women (73.8%) were in remission phase and 4 (26.7%) had active disease at the time of conception. The time interval between disease diagnosis and the index pregnancy was 4.2 +/- 2.5 years. Two patients with renal involvement had lupus flare-up during the antenatal period. There was no case of lupus flare-up in the postpartum period. Gestational age at delivery was significantly lower in SLE patients (35.9 +/- 2.5 weeks) compared to the control group (37.4 +/- 2.2 weeks). The incidence of intrauterine growth retardation was significantly higher in the SLE patients (40%). There was no case of neonatal lupus or congenital heart block.
N Aggarwal; H Sawhney; K Vasishta; S Chopra; P Bambery
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  39     ISSN:  0004-8666     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-05-20     Completed Date:  1999-05-20     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  28-30     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Nehru Hospital, Chandigarh, India.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Case-Control Studies
Delivery, Obstetric / methods
Fetal Growth Retardation / etiology
Lupus Erythematosus, Systemic / complications*,  drug therapy
Pregnancy Complications* / drug therapy
Pregnancy Outcome*
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Steroids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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