Document Detail


Pregnancy in patients with myelodysplastic syndromes (MDS).
MedLine Citation:
PMID:  18374412     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report 6 pregnancies in 5 females with low-risk myelodysplastic syndromes (MDS) (median age at diagnosis 28 years, range 26-29) observed in the last 15 years. In 2 cases pregnancy was concomitant to the diagnosis of MDS, in the remaining 4 cases the intervals from diagnosis were 2, 3, 4 and 9 years, respectively. One patient had a foetal growth retardation corrected with steroid treatment while the remaining 5 pregnancies were uneventful. After a median time from delivery of 104 months (range 18-187) none of the patients developed acute myeloid leukemia (AML) and all are alive in stable disease. In conclusion, selected females with low-risk MDS could not be discouraged to have full term pregnancies.
Authors:
P Volpicelli; R Latagliata; M Breccia; I Carmosino; C Stefanizzi; L Napoleone; F Vozella; A Levi; F Natalino; G Alimena
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-03-28
Journal Detail:
Title:  Leukemia research     Volume:  32     ISSN:  0145-2126     ISO Abbreviation:  Leuk. Res.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-06-13     Completed Date:  2008-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7706787     Medline TA:  Leuk Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1605-7     Citation Subset:  IM    
Affiliation:
Dipartimento di Biotecnologie Cellulari ed Ematologia, Università La Sapienza di Roma, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Female
Humans
Myelodysplastic Syndromes / diagnosis*
Pregnancy
Pregnancy Complications, Hematologic / diagnosis*
Pregnancy Outcome

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