Document Detail

Pregnancy in liver cirrhosis and/or portal hypertension.
MedLine Citation:
PMID:  327818     Owner:  NLM     Status:  MEDLINE    
Clinical features of pregnancy in women with liver cirrhosis and/or portal hypertension have been reviewed. Termination of pregnancy is seldom indicated in a woman with compensated cirrhosis or a young woman with extrahepatic venous obstruction. However, the risk of spontaneous abortion is increased in cirrhotic women without shunt even if there is no deterioration of liver function. The risk of bleeding from esophageal varices or deterioration of liver function is usually unpredictable. Shunt surgery can be done with relatively little effect on both the mother and the fetus if conservative measurements fail to control the hematemesis. Vaginal delivery can be anticipated in most women, and cesarean section should be preserved for obstetric indications. The risk of postpartum hemorrhage is greatly increased, particularly in patients with previous shunt surgery. Perinatal loss is high because of the increased rate of premature delivery and stillbirth. Maternal prognosis is grave in women with cirrhosis.
Y S Cheng
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  128     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-09-02     Completed Date:  1977-09-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  812-22     Citation Subset:  AIM; IM    
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MeSH Terms
Abortion, Spontaneous / etiology
Delivery, Obstetric / methods
Esophageal and Gastric Varices / etiology
Fetal Death / etiology
Gastrointestinal Hemorrhage / etiology
Hypertension, Portal / complications,  etiology,  surgery*
Liver / physiopathology
Liver Cirrhosis / complications,  surgery*
Maternal Mortality
Pregnancy Complications / surgery*
Pregnancy Complications, Cardiovascular
Pregnancy Trimester, Second
Time Factors
Vascular Diseases / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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