Document Detail


Pregnancy in kidney transplant recipients.
MedLine Citation:
PMID:  16213315     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Our aim was to investigate kidney allograft, obstetric, and maternal outcomes in pregnant women undergoing kidney transplantation in our center. METHODS: Retrospective data on 74 pregnancies in 60 patients were reviewed and completed through phone interviews were compared with information on a control group of female kidney recipients. RESULTS: Mean age of patients at transplantation was 26.55 +/- 4.72 years and the median interval between transplantation and pregnancy was 27.5 months. Gestational period was 8 months. Live birth was the outcome in 43.2% of pregnancies; 9.5% led to still birth, 24.3% were aborted, and obstetrical data of the remaining were unavailable. Among the 11 patients who became pregnant within 12 months after transplantation, we observed seven live births and four abortions. None of pregnancies that were accompanied by acute rejection episodes (ARE) were successful. Twenty-six patients experienced at least one ARE versus 23 patients of the control group (P = NS). However, the first ARE occurred later in the pregnant group (P = .028). Chronic rejection and graft loss were seen in 24 and 18 study group cases and 17 and 17 control cases, respectively (P = NS). One-, 3-, 5-, and 10-year graft survivals were 100%, 96.5%, 94.5%, and 77.1% in the pregnant group versus 93.2%, 85.7%, 81%, and 64.7% in the control group, respectively (P = .07). CONCLUSION: Pregnancy in kidney recipients seems to be safe for kidney allograft recipients even within the first year posttransplant. Nonetheless, the outcomes of pregnancy in this group of patients is not always favorable, especially when rejection occurs simultaneously.
Authors:
F Pour-Reza-Gholi; M Nafar; F Farrokhi; A Entezari; N Taha; A Firouzan; B Einollahi
Related Documents :
6586395 - Randomized trial of intracervical prostaglandin e2 gel and intraamniotic prostaglandin ...
24699265 - A bioplex analysis of cytokines and chemokines in first trimester maternal plasma to sc...
7486395 - Abortions, fetal death, and stillbirths in pregnant pygmy goats inoculated with tachyzo...
1003395 - Current concepts of defibrination in the pregnant woman.
15589875 - Normal birth after single-embryo transfer in a patient with excessive polypronuclear zy...
2575045 - The effect of hypertension in pregnancy on fetal and neonatal condition.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplantation proceedings     Volume:  37     ISSN:  0041-1345     ISO Abbreviation:  Transplant. Proc.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-10-10     Completed Date:  2006-01-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243532     Medline TA:  Transplant Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3090-2     Citation Subset:  IM    
Affiliation:
Urology and Nephrology Research Center, Shaheed Labbafinejad Medical Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abortion, Induced
Female
Graft Rejection / epidemiology
Graft Survival / physiology
Humans
Kidney Transplantation / immunology,  physiology*
Pregnancy
Pregnancy Outcome / epidemiology*
Retrospective Studies
Transplantation, Homologous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Erectile function in end-stage renal disease before and after renal transplantation.
Next Document:  High incidence of early posttransplantation diabetes mellitus in an eastern population.