| Pregnancy in idiopathic aplastic anemia (report of 10 patients). | |
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MedLine Citation:
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PMID: 1618358 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper reports on 6 patients with severe, 2 with moderate and 2 with mild aplastic anemia who had a total of 18 pregnancies after the diagnosis. All four pregnancies that occurred during the active state of severe and moderate aplastic anemias were electively terminated. Two out of 14 pregnancies that occurred during the long-term remission were electively terminated for non-medical reason, two spontaneous abortions occurred and 10 live births were seen. All offspring were healthy at follow-up. During pregnancy the circulating blood cell levels decreased in 1 out of 6 pregnancies in patients who were in remission from mild and moderate aplastic anemias, and in 4 out of 8 pregnancies in patients who were in remission from severe aplastic anemia. In all 5 cases that showed a relapse during pregnancy the remission recurred following the termination of pregnancy. The data presented suggest that aplastic anemia in long-term remission can unpredictably relapse during pregnancy, but its final outcome appears not to be affected by pregnancy. Furthermore, there is no correlation between the pre-pregnancy clinical course and the events during pregnancy. The outcome of pregnancy during the remission of aplastic anemia seems beneficial, and spontaneous delivery should be preferred. |
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Authors:
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A Pajor; E Kelemen; Z Szakács; D Lehoczky |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 45 ISSN: 0301-2115 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 1992 Jun |
Date Detail:
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Created Date: 1992-08-04 Completed Date: 1992-08-04 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 19-25 Citation Subset: IM |
Affiliation:
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2nd Department of Obstetrics and Gynecology, Semmelweis University Medical School, Budapest, Hungary. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Therapeutic Anemia, Aplastic / blood* Female Humans Pregnancy Pregnancy Complications, Hematologic / blood* Pregnancy Outcome* Remission, Spontaneous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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