| Pregnancy in a case of Nelson's syndrome. | |
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MedLine Citation:
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PMID: 696256 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A woman suffering from Cushing's disease from the age of 17 who had been treated consecutively with pituitary irradiation, bilateral partial adrenalectomy and o,p'-DDD (Mitotane, USP) presented the clinical picture of Nelson's syndrome (hypoadrenalism with secondary hypersecretion of ACTH and MSH) at the age of 32. Under substitution therapy with corticoids she became pregnant for the first time at the age of 38. The course of the pregnancy was normal and at term she was delivered of a normal child by Cesarean section. The materno-fetal relationship, the increased risk of pituitary infarction during pregnancy and the possible teratogenic effect of chemotherapy in such cases are discussed. |
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Authors:
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S Leiba; H Kaufman; G Winkelsberg; C M Bahary |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 57 ISSN: 0001-6349 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 1978 |
Date Detail:
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Created Date: 1978-11-18 Completed Date: 1978-11-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 373-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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therapeutic use Adult Female Humans Nelson Syndrome* / drug therapy, metabolism Pituitary Neoplasms* / drug therapy Pregnancy Pregnancy Complications* / drug therapy, metabolism |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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