Document Detail


Pregnancy in Wegener's granulomatosis: successful treatment with intravenous immunoglobulin.
MedLine Citation:
PMID:  15801073     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present the case of a women diagnosed with Wegener's disease at the age of 26 years, refractory to corticosteroid and cyclophosphamide therapy. Treatment with intravenous immunoglobulin (IVIg) was started, leading to partial clinical remission of disease. During IVIg treatment she became pregnant. IVIg therapy was continued, the disease went into remission, and after 40 weeks the patient delivered a healthy boy. After 6 months from the delivery, the patient became pregnant again. Now she is at the 22nd week of pregnancy and she is doing very well. This case supports the beneficial effect of IVIg in Wegener's granulomatosis and illustrates its safety and efficacy during pregnancy.
Authors:
Francesca Bellisai; Gabriella Morozzi; Roberto Marcolongo; Mauro Galeazzi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical rheumatology     Volume:  23     ISSN:  0770-3198     ISO Abbreviation:  Clin. Rheumatol.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2005-03-31     Completed Date:  2005-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8211469     Medline TA:  Clin Rheumatol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  533-5     Citation Subset:  IM    
Affiliation:
Dipartimento di Medicina Clinica e Scienze Immunologiche-Sezione di Reumatologia, Policlinico Le Scotte, University of Siena, Viale Bracci, 53100 Siena, Italy. francescabellisai@yahoo.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Humans
Immunoglobulins, Intravenous / therapeutic use*
Immunosuppressive Agents / therapeutic use*
Pregnancy
Pregnancy Complications / drug therapy*
Treatment Outcome
Wegener Granulomatosis / drug therapy*
Chemical
Reg. No./Substance:
0/Immunoglobulins, Intravenous; 0/Immunosuppressive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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