Document Detail

Pregnancy in 20 patients with bioprosthetic valve replacement.
MedLine Citation:
PMID:  6861544     Owner:  NLM     Status:  MEDLINE    
We studied twenty women who became pregnant after porcine bioprosthetic valve replacement. Six patients had aortic valve, seven mitral, and seven aortic plus mitral valve replacement. All women were treated with aspirin (1 g daily or 500 mg every 48 hours) during pregnancy, delivery, and the postdelivery period. Thirteen patients experienced atrial fibrillation. There were 27 pregnancies with three ending in abortion. Twenty five normal babies were delivered. There was no maternal mortality or morbidity from thromboembolism or hemorrhage. Comparison of the pregnancy course of these women and the general population shows no difference with respect to fetal or maternal morbidity and mortality. Pregnant women with bioprosthetic valve replacement treated with aspirin had normal pregnancies without the risk of thromboembolism. Fetal and perinatal morbidity and mortality was also within normal limits.
L Nuñez; J L Larrea; M Gil Aguado; J A Reque; R Matorras; J A Minguez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  84     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1983 Jul 
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  26-8     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Valve
Aspirin / therapeutic use*
Fetus / drug effects
Heart Valve Prosthesis*
Mitral Valve
Pregnancy Complications, Cardiovascular / prevention & control*
Thromboembolism / prevention & control*
Reg. No./Substance:

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