Document Detail

Pregnancy and hereditary spherocytosis. Report of 8 patients and a review.
MedLine Citation:
PMID:  8328819     Owner:  NLM     Status:  MEDLINE    
As there is only little information on pregnancy complicated by hereditary spherocytosis, we report on 8 patients with this disorder who had a total of 19 pregnancies. 10 pregnancies occurred in patients before splenectomy, and 9 occurred after splenectomy. There were 13 term births, 4 spontaneous abortions and 2 therapeutic abortions. Of the 19 pregnancies, 8 were complicated by anemia and all were in patients without splenectomy. A hemolytic crisis was encountered in 6 pregnancies, and persistent anemia occurred in 2. Transfusion was required in 4 pregnancies. It would appear that pregnancy may precipitate hemolytic anemia but maternal morbidity and fetal outcome seem more favorable after splenectomy than before splenectomy.
A Pajor; D Lehoczky; Z Szakács
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  253     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  1993  
Date Detail:
Created Date:  1993-08-12     Completed Date:  1993-08-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  37-42     Citation Subset:  IM    
2nd Department of Obstetrics and Gynecology, Semmelweis Medical University, Budapest, Hungary.
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MeSH Terms
Abortion, Induced
Abortion, Spontaneous / etiology
Follow-Up Studies
Infant, Newborn
Pregnancy Complications, Hematologic / diagnosis,  therapy*
Retrospective Studies
Spherocytosis, Hereditary / genetics,  therapy*

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