Document Detail

Pregnancy following transsphenoidal resection of prolactin-secreting pituitary tumors.
MedLine Citation:
PMID:  6834116     Owner:  NLM     Status:  MEDLINE    
This report describes 200 women in the childbearing age group with prolactin-secreting pituitary adenomas treated by transsphenoidal microsurgery. There were 136 patients with microadenomas (10 mm or less in diameter), 30 with macroadenomas, 11 with invasive adenomas, and one with hyperplasia. The overall rate for postoperative normalization of serum prolactin was 57%, and it was 72% for those patients with microadenomas. Pregnancy was desired by 90 women, and 78 (84%) became pregnant, although 10 required postoperative bromocriptine to do so. Serious postoperative complications were rare, and produced no major morbidity. The results of surgery were most favorable in women with microadenomas and preoperative serum prolactin levels of 100 ng/ml or less.
E R Laws; N C Fode; R V Randall; C F Abboud; C B Coulam
Related Documents :
2039426 - Neuroendocrinology of the hypothalamo-pituitary-adrenal axis in pregnancy and the puerp...
17342026 - Prenatal diagnosis and treatment of congenital adrenal hyperplasia.
1607056 - Long-term effects of time, medical treatment and pregnancy in 176 hyperprolactinemic wo...
6535306 - Enzyme histochemical and ultrastructural studies in human adrenal glands of normal and ...
9043926 - A prospective, longitudinal study of emotions and relationships in in-vitro fertilizati...
6932206 - Single dose extra-amniotic prostaglandin gel for midtrimester termination of pregnancy.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  58     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  685-8     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenoma / drug therapy,  secretion,  surgery*
Bromocriptine / therapeutic use
Pituitary Neoplasms / drug therapy,  secretion,  surgery*
Postoperative Complications
Prolactin / secretion*
Reg. No./Substance:
25614-03-3/Bromocriptine; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Arterial blood supply of the normal human pituitary gland. An anatomical study.
Next Document:  Creatine kinase isoenzymes in severe head injury.