Document Detail


Pregnancy following transsphenoidal resection of prolactin-secreting pituitary tumors.
MedLine Citation:
PMID:  6834116     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report describes 200 women in the childbearing age group with prolactin-secreting pituitary adenomas treated by transsphenoidal microsurgery. There were 136 patients with microadenomas (10 mm or less in diameter), 30 with macroadenomas, 11 with invasive adenomas, and one with hyperplasia. The overall rate for postoperative normalization of serum prolactin was 57%, and it was 72% for those patients with microadenomas. Pregnancy was desired by 90 women, and 78 (84%) became pregnant, although 10 required postoperative bromocriptine to do so. Serious postoperative complications were rare, and produced no major morbidity. The results of surgery were most favorable in women with microadenomas and preoperative serum prolactin levels of 100 ng/ml or less.
Authors:
E R Laws; N C Fode; R V Randall; C F Abboud; C B Coulam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  58     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  685-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adenoma / drug therapy,  secretion,  surgery*
Adolescent
Adult
Bromocriptine / therapeutic use
Female
Humans
Pituitary Neoplasms / drug therapy,  secretion,  surgery*
Postoperative Complications
Pregnancy*
Prolactin / secretion*
Chemical
Reg. No./Substance:
25614-03-3/Bromocriptine; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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