| Pregnancy and economic outcomes in patients treated for recurrent preterm labor. | |
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MedLine Citation:
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PMID: 14999214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To compare clinical and cost-effectiveness of treating recurrent preterm labor (RPTL) with oral nifedipine versus continuous subcutaneous terbutaline infusion (SQT). STUDY DESIGN: Women with singleton gestations prescribed nifedipine for tocolysis following first diagnosis of preterm labor were identified. Women hospitalized with RPTL at <34 weeks were matched by gestational age (GA) after resuming nifedipine (NIF group) with women prescribed SQT (SQT group) after stabilization. Healthcare utilization costs were modeled and compared. RESULTS: This study analyzed 142 matched pairs. GA at RPTL (matched variable) was 30.4+/-2.6 weeks. GA at delivery was earlier in the NIF group versus the SQT group (35.7+/-3.1 weeks versus 36.6+/-2.1 weeks, p=0.004). Overall, infants from the NIF group had lower birth weights and higher nursery days than infants from the SQT group. Healthcare utilization costs were greater in the NIF group versus the SQT group (37,040+/-47,518 US dollars versus 26,546+/-25,386 US dollars, p=0.014). CONCLUSION: Treating RPTL with SQT versus oral nifedipine resulted in a later GA at delivery, improved neonatal outcome, and increased cost-effectiveness. |
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Authors:
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Alfred Fleming; Robert Bonebrake; Niki Istwan; Debbie Rhea; Suzanne Coleman; Gary Stanziano |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 24 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-04-06 Completed Date: 2004-07-15 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 223-7 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Creighton University Medical Center, Omaha, NE 68131, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Adult Case-Control Studies Cost-Benefit Analysis Costs and Cost Analysis Female Humans Infusion Pumps, Implantable Nifedipine / administration & dosage, therapeutic use* Obstetric Labor, Premature / economics*, prevention & control* Pregnancy Pregnancy Outcome* Recurrence Retrospective Studies Terbutaline / administration & dosage, therapeutic use* Tocolysis / economics*, methods Tocolytic Agents / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Tocolytic Agents; 21829-25-4/Nifedipine; 23031-25-6/Terbutaline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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