| Pregnancy during TNFalpha antagonist therapy: beware the rifampin-oral contraceptive interaction. Report of two cases. | |
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MedLine Citation:
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PMID: 20447852 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report two cases of pregnancy in patients taking TNFalpha antagonists for chronic inflammatory joint disease. A factor in both pregnancies was the use of rifampin concomitantly with a combined oral contraceptive. Both patients were taking rifampin and isoniazid for tuberculosis prophylaxis in compliance with French recommendations for patients with positive intradermal tuberculin tests who are scheduled to receive biotherapeutic agents. |
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Authors:
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Cécile Wibaux; Irina Andrei; Julien Paccou; Peggy Philippe; Emmanuel Biver; Bernard Duquesnoy; René Marc Flipo |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-05-05 |
Journal Detail:
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Title: Joint, bone, spine : revue du rhumatisme Volume: 77 ISSN: 1778-7254 ISO Abbreviation: Joint Bone Spine Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-25 Completed Date: 2010-08-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100938016 Medline TA: Joint Bone Spine Country: France |
Other Details:
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Languages: eng Pagination: 268-70 Citation Subset: IM |
Copyright Information:
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Copyright 2010. Published by Elsevier SAS. |
Affiliation:
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Service de rhumatologie, hôpital Roger-Salengro, CHRU de Lille, université de Lille-2, rue Emile-Laine, 59037 Lille cedex, France. c-wibaux@chru-lille.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antirheumatic Agents / adverse effects* Antitubercular Agents / adverse effects* Contraceptives, Oral / adverse effects* Drug Interactions Female Humans Immunocompromised Host Isoniazid / adverse effects Pregnancy Rifampin / adverse effects* Spondylitis, Ankylosing / drug therapy*, immunology Tuberculosis, Pulmonary / immunology, prevention & control* Tumor Necrosis Factor-alpha / antagonists & inhibitors |
| Chemical | |
Reg. No./Substance:
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0/Antirheumatic Agents; 0/Antitubercular Agents; 0/Contraceptives, Oral; 0/Tumor Necrosis Factor-alpha; 13292-46-1/Rifampin; 54-85-3/Isoniazid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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