Document Detail

Pregnancy and delivery in patients with enterostomy due to anorectal complications from Crohn's disease.
MedLine Citation:
PMID:  16715249     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIMS: Enterostomy is often undergone by patients with Crohn's disease (CD) due to severe anorectal lesions such as rectovaginal fistula (RVF). Reports of successful pregnancy and delivery, which are important determinants of quality of life for female CD patients with stoma, are limited. Thus, we investigated problems associated with pregnancy and delivery in female CD patients at our hospital. MATERIALS AND METHODS: Between 1985 and 2003, five female CD patients with enterostoma carried seven pregnancies and delivered eight babies in our hospital. For this study, we investigated CD activity, fetal growth, stoma complications, and the outcome of delivery in these seven pregnancies. RESULTS: Among the five patients, four underwent loop ileostomy and one loop sigmoidostomy for treatment of RVF or severe stricture of the rectum or sigmoid colon. Except for one case, no fertility treatment was done. During pregnancy, a flare-up was observed in one patient and was successfully treated with corticosteroids. Although home enteral or parenteral nutrition was required in two cases, fetal growth was within the normal range in all pregnancies. Preterm delivery occurred in one case with a twin pregnancy. The mean diameter of stoma increased during pregnancy (p<0.01), and a mucosal laceration of stoma by the edge of an ostomy appliance occurred in one case. All deliveries were safe, with six cesarean sections and one transvaginal delivery. After each delivery, the stoma returned to pre-pregnancy size. CONCLUSIONS: Pregnancy and delivery in CD patients with stoma is safe and should be encouraged. However, special attention to disease activity, nutritional support, and stoma-related complications is recommended.
Ken-ichi Takahashi; Yuji Funayama; Kouhei Fukushima; Chikashi Shibata; Hitoshi Ogawa; Eiko Kumagai; Iwao Sasaki
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Publication Detail:
Type:  Journal Article     Date:  2006-05-20
Journal Detail:
Title:  International journal of colorectal disease     Volume:  22     ISSN:  0179-1958     ISO Abbreviation:  Int J Colorectal Dis     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-01-11     Completed Date:  2007-11-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607899     Medline TA:  Int J Colorectal Dis     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  313-8     Citation Subset:  IM    
Department of Surgery, Division of Gastrointestinal and Colorectal Surgery, Tohoku University Graduate School of Medicine, and Wound, Ostomy, and Continence Center, Tohoku University Hospital, Sendai, 980-8574, Japan.
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MeSH Terms
Crohn Disease / complications*,  therapy
Delivery, Obstetric*
Nutritional Support
Pregnancy Complications*
Pregnancy Outcome
Rectal Diseases / etiology,  surgery*

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