Document Detail


Pregnancy complicated by autoimmune polyglandular syndrome type II: a case report.
MedLine Citation:
PMID:  9642614     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Autoimmune polyglandular syndrome may complicate pregnancy and be confused with hyperemesis gravidarum as a cause of hypoglycemia and electrolyte imbalance in the first trimester of pregnancy. Autoimmune polyglandular syndromes are uncommon disorders characterized by the development and presentation of multiple endocrine and organ dysfunction. To our knowledge, we present the first case of an autoimmune polyglandular syndrome complicating pregnancy. A 26-year-old woman, gravida 5 para 3 at 12 weeks gestation, presented with hyperemesis and signs and symptoms consistent with adrenal insufficiency and hypothyroidism. Evaluation revealed autoimmune polyglandular syndrome type II. Autoimmune polyglandular syndromes are a myriad group of diseases characterized by polyglandular dysfunction. These syndromes should be kept in mind when dealing with pregnant patients presenting with hyperemesis and an electrolyte imbalance who do not improve with the usual treatment for hyperemesis. An endocrine dysfunction such as polyglandular syndrome may exist.
Authors:
K Gaither; R Wright; J J Apuzzio; L Gittens; V Ganesh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of maternal-fetal medicine     Volume:  7     ISSN:  1057-0802     ISO Abbreviation:  J Matern Fetal Med     Publication Date:    1998 May-Jun
Date Detail:
Created Date:  1998-09-01     Completed Date:  1998-09-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9211288     Medline TA:  J Matern Fetal Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  154-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, U.M.D.N.J.-New Jersey Medical School, Newark 07103-2714, USA.
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MeSH Terms
Descriptor/Qualifier:
Addison Disease / complications,  drug therapy
Adult
Anti-Inflammatory Agents / therapeutic use
Female
Humans
Hydrocortisone / therapeutic use
Hypothyroidism / complications,  drug therapy
Polyendocrinopathies, Autoimmune / complications*,  drug therapy
Pregnancy
Pregnancy Complications* / drug therapy
Thyroxine / therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 50-23-7/Hydrocortisone; 7488-70-2/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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