Document Detail

Pregnancy complicated by the May-Hegglin anomaly.
MedLine Citation:
PMID:  8229617     Owner:  NLM     Status:  MEDLINE    
May-Hegglin anomaly is a prepotent autosomal hereditary disease characterized by giant thrombocytes, thrombocytopenia and continuous appearance of inclusion bodies (Döhle like corpuscle) in the cytoplasm of granulocytes. In this report we report our experience of a case whose pregnancy was complicated by this disease. This anomaly is rare and there are only 15 families reported in this country. The only clinical symptom is the tendency to bleed, but since this is not rare, it may be necessary to consider examination of peripheral blood in every case of thrombocytopenia. If this disease complicates pregnancy, it is important to plan the mode of delivery to consider both the maternal and fetal prognosis.
A Ishii; T Honnma; M Ishida; F Sano; H Hamada; M Takayanagi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  21     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  1993  
Date Detail:
Created Date:  1993-12-03     Completed Date:  1993-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  247-52     Citation Subset:  IM    
Department of Obstetrics and Gynecology, St. Marianna University School of Medicine, Kawasaki, Japan.
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MeSH Terms
Blood Platelets / pathology*
Cytoplasm / pathology
Granulocytes / pathology*
Pregnancy Complications, Hematologic / blood*
Thrombocytopenia* / complications*

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