| Pregnancy and birth after kidney donation: the Norwegian experience. | |
| | |
MedLine Citation:
|
PMID: 18853953 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Reports on pregnancies in kidney donors are scarce. The aim was to assess pregnancy outcomes for previous donors nationwide. The Medical Birth Registry of Norway holds records of births since 1967. Linkage with the Norwegian Renal Registry provided data on pregnancies of kidney donors 1967-2002. A random sample from the Medical Birth Registry was control group, as was pregnancies in kidney donors prior to donation. Differences between groups were assessed by two-sided Fisher's exact tests and with generalized linear mixed models (GLMM). We identified 326 donors with 726 pregnancies, 106 after donation. In unadjusted analysis (Fisher) no differences were observed in the occurrence of preeclampsia (p = 0.22). In the adjusted analysis (GLMM) it was more common in pregnancies after donation, 6/106 (5.7%), than in pregnancies before donation 16/620 (2.6%) (p = 0.026). The occurrence of stillbirths after donation was 3/106 (2.8%), before donation 7/620 (1.1%), in controls (1.1%) (p = 0.17). No differences were observed in the occurrence of adverse pregnancy outcome in kidney donors and in the general population in unadjusted analysis. Our finding of more frequent preeclampsia in pregnancies after kidney donation in the secondary analysis must be interpreted with caution, as the number of events was low. |
| | |
Authors:
|
A V Reisaeter; J Røislien; T Henriksen; L M Irgens; A Hartmann |
Related Documents
:
|
12969713 - Successful intracytoplasmic sperm injection after failed in vitro fertilization due to ... 2226913 - Oocyte retention after follicle luteinization. 8417593 - An update on new york city's dramatic increase in low birthweights. |
Publication Detail:
|
Type: Journal Article Date: 2008-10-06 |
Journal Detail:
|
Title: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Volume: 9 ISSN: 1600-6143 ISO Abbreviation: Am. J. Transplant. Publication Date: 2009 Apr |
Date Detail:
|
Created Date: 2009-04-06 Completed Date: 2009-07-29 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100968638 Medline TA: Am J Transplant Country: Denmark |
Other Details:
|
Languages: eng Pagination: 820-4 Citation Subset: IM |
Affiliation:
|
Department of Medicine, Section of Nephrology, Rikshospitalet, University of Oslo, Norway. anna.varberg.reisaeter@rikshospitalet.no |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Female Fetal Development / physiology* Humans Living Donors* Nephrectomy / adverse effects* Norway / epidemiology Parity Pre-Eclampsia / epidemiology* Pregnancy Pregnancy Complications / epidemiology* Pregnancy Outcome Premature Birth / epidemiology* Reference Values Reproducibility of Results |
| Comments/Corrections | |
Comment In:
|
Am J Transplant. 2009 Apr;9(4):661-8
[PMID:
19344459
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Posttransplant HLA alloreactivity in stable kidney transplant recipients-incidences and impact on lo...
Next Document: Polyfunctional cytomegalovirus-specific CD4+ and pp65 CD8+ T cells protect against high-level replic...