Document Detail

Pregnancy attenuates activity of the baroreceptor reflex.
MedLine Citation:
PMID:  7621609     Owner:  NLM     Status:  MEDLINE    
1. Pregnancy-induced changes in acute blood pressure regulation are reviewed. 2. Pregnant animals are less able to maintain arterial pressure during haemorrhage than non-pregnant animals. 3. Baroreceptor reflex-mediated increases in heart rate, renal sympathetic activity, vasopressin, ACTH and cortisol are reduced during pregnancy. Therefore, one explanation for the subnormal ability of pregnant animals to regulate arterial pressure during haemorrhage is that the baroreceptor reflex is not as effective. 4. Chronic increases in oestrogen levels in non-pregnant rabbits do not reduce the gain of baroreflex control of renal sympathetic activity. This and other findings suggest that oestrogen alone does not mediate the blunted baroreflex activity observed during pregnancy.
V L Brooks; R R Quesnell; S R Cumbee; V S Bishop
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Clinical and experimental pharmacology & physiology     Volume:  22     ISSN:  0305-1870     ISO Abbreviation:  Clin. Exp. Pharmacol. Physiol.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-08-29     Completed Date:  1995-08-29     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0425076     Medline TA:  Clin Exp Pharmacol Physiol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  152-6     Citation Subset:  IM    
Department of Physiology, Oregon Health Sciences University, Portland 97201-3098, USA.
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MeSH Terms
Baroreflex / physiology*
Blood Pressure
Heart Rate
Pregnancy, Animal / physiology*
Time Factors
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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