| Pregnancy-associated liver disorders. | |
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MedLine Citation:
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PMID: 18256934 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Liver disorders associated with pregnancy include hyperemesis gravidarum (HG), intrahepatic cholestasis of pregnancy (ICP), preeclampsia, syndrome of hemolysis, elevated liver enzymes and low platelets (HELLP), and acute fatty liver of pregnancy (AFLP). These conditions are relatively common and unique to pregnancy and are more likely to occur at certain terms of gestation specific to each condition. They can be associated with significant maternal and fetal morbidity and mortality. Although managing such patients may be very challenging, spontaneous resolution of the disease occurs shortly after termination of the pregnancy, usually without hepatic sequellae. Early diagnosis and timely treatment is a key to therapeutic success. This article explores the clinical features, pathophysiology, and management of these disorders. |
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Authors:
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Iryna S Hepburn; Robert R Schade |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2008-02-07 |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 53 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-20 Completed Date: 2008-10-14 Revised Date: 2008-10-20 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 2334-58 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA. ihepburn@mail.mcg.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cholestasis, Intrahepatic / diagnosis, drug therapy, physiopathology Diagnosis, Differential Fatty Liver / diagnosis, drug therapy, physiopathology Female HELLP Syndrome / diagnosis, drug therapy, physiopathology Humans Hyperemesis Gravidarum / diagnosis, drug therapy, physiopathology Liver Diseases / diagnosis, drug therapy, physiopathology* Pregnancy Pregnancy Complications / diagnosis, drug therapy, physiopathology* |
| Comments/Corrections | |
Erratum In:
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Dig Dis Sci. 2008 Oct;53(10):2836 Note: Schade, Robert R [added] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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