Document Detail

Pregnancy - associated glycoproteins as a new diagnostic tool in cattle reproduction.
MedLine Citation:
PMID:  19946848     Owner:  NLM     Status:  MEDLINE    
Pregnancy-associated glycoproteins (PAGs) are powerful pregnancy markers in domestic cattle. These proteins are expressed in mono- and binucleate trophoblast cells from the first days of gestation until calving. Different molecules were identified as being expressed at various stages of pregnancy. However, up to date, their functions and activities during pregnancy were not yet established. Specific RIA tests were developed (classic and alternative RIA) and used to measure the concentration of these glycoproteins in blood during gestation and the postpartum period in cattle. In maternal blood, PAGs rise to detectable levels from days 24 to 28 after fertilization. A recent study indicated that PAGs can also be detected in milk samples. However, concentrations in milk are much lower when compared to those of plasma.
Z Gajewski; M Pertajitis; N Sousa; J Beckers; B Pawli?ski; F Janett
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Schweizer Archiv f?r Tierheilkunde     Volume:  151     ISSN:  0036-7281     ISO Abbreviation:  Schweiz. Arch. Tierheilkd.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-30     Completed Date:  2010-04-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0424247     Medline TA:  Schweiz Arch Tierheilkd     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  577-82     Citation Subset:  IM    
Department of Clinical Sciences, Faculty of Veterinary Medicine, WULS, Warsaw, Poland.
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MeSH Terms
Pregnancy, Animal / blood*
Pregnancy-Associated alpha 2-Macroglobulins / analysis*
Radioimmunoassay / methods
Reg. No./Substance:
0/Pregnancy-Associated alpha 2-Macroglobulins

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