Document Detail

Pregnancy-associated Cushing's syndrome secondary to a luteinizing hormone/human chorionic gonadotropin receptor-positive adrenal carcinoma.
MedLine Citation:
PMID:  12587537     Owner:  NLM     Status:  MEDLINE    
Cushing's syndrome occurring during pregnancy is frequently due to an adrenal neoplasm. Adrenal gland tumors occasionally respond to luteinizing hormone (LH) or human chorionic gonadotropin (hCG). We report a case of Cushing's syndrome during and following pregnancy due to an adrenal carcinoma which expressed the LH/hCG receptor. The presence of these receptors may have led to the growth and function of the tumor during pregnancy.
L A Wy; H E Carlson; P Kane; X Li; Z M Lei; C V Rao
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  16     ISSN:  0951-3590     ISO Abbreviation:  Gynecol. Endocrinol.     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2003-02-17     Completed Date:  2003-03-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  413-7     Citation Subset:  IM    
Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY 11794-8154, USA.
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MeSH Terms
Adrenal Gland Neoplasms / chemistry,  complications*
Carcinoma / chemistry,  complications*
Cushing Syndrome / etiology*
In Situ Hybridization
Pregnancy Complications, Neoplastic*
RNA, Messenger / analysis
Receptors, LH / analysis*,  genetics
Reg. No./Substance:
0/RNA, Messenger; 0/Receptors, LH

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