Document Detail


Pregnancy after tumor debulking and intraperitoneal cisplatin for appendiceal carcinoid tumor.
MedLine Citation:
PMID:  17666634     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Pregnancy after cytoreductive surgery and intraperitoneal chemotherapy is rare. CASE: We present the case of a 25-year-old woman with appendiceal carcinoid tumor treated with intraperitoneal cisplatin for peritoneal recurrence after a fertility-sparing cytoreductive procedure. Five years after her procedure, she conceived with the help of assisted reproductive technologies and delivered a viable term fetus via cesarean delivery. She subsequently had a successful second pregnancy and is currently alive without evidence of her disease. CONCLUSION: Conception is possible after tumor debulking and intraperitoneal chemotherapy. In unique clinical situations, fertility-sparing surgery may be considered in young patients who desire future pregnancy.
Authors:
Gina M Mantia Smaldone; Scott D Richard; Thomas C Krivak; Joseph L Kelley; Robert P Edwards
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  110     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-01     Completed Date:  2007-09-06     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  477-9     Citation Subset:  AIM; IM    
Affiliation:
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. mantiagm@upmc.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Antineoplastic Agents / administration & dosage,  adverse effects*,  therapeutic use
Appendiceal Neoplasms / drug therapy*,  surgery
Carcinoid Tumor / drug therapy*,  surgery
Cisplatin / administration & dosage,  adverse effects*,  therapeutic use
Combined Modality Therapy
Female
Humans
Infertility, Female / chemically induced,  therapy*
Infusions, Parenteral
Neoplasm Recurrence, Local / drug therapy*
Pregnancy
Pregnancy Complications, Neoplastic
Pregnancy Outcome
Reproductive Techniques, Assisted
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 15663-27-1/Cisplatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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