Document Detail

Pregnancy and Takayasu arteritis: a single centre experience from North India.
MedLine Citation:
PMID:  20598031     Owner:  NLM     Status:  MEDLINE    
AIM: Takayasu's syndrome is a chronic inflammatory arteriopathy of unknown origin which primarily affects women of reproductive age. We report the course and outcome of 37 pregnancies in 15 women with Takayasu arteritis during the period 1999-2008.
METHODS: A retrospective analysis of 9 years was carried out in a tertiary hospital in Northern India. The effect of disease on the course of pregnancy, complications during pregnancy and perinatal outcome were analyzed.
RESULTS: Hypertension was the most common presenting feature (27%). In the majority of the patients, vessels involved were the subclavian artery and arch of the aorta. Superimposed preeclampsia complicated 62% of pregnancies while 16% of pregnancies had intrauterine growth retardation. Six patients had preterm delivery and one had preeclampsia and placental abruption. The mean gestational age at delivery was 36 +/- 3 weeks. The majority of the patients had a vaginal delivery. There was one maternal death due to accelerated hypertension and its complications.
CONCLUSION: Adequate control of blood pressure during pregnancy, planning the timing and mode of the delivery and vigilant monitoring during intrapartum period with special reference to management of blood pressure and its complications is essential for an optimum outcome.
Vanita Suri; Neelam Aggarwal; Anish Keepanasseril; Seema Chopra; Rajesh Vijayvergiya; Sanjay Jain
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  36     ISSN:  1447-0756     ISO Abbreviation:  J. Obstet. Gynaecol. Res.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-05     Completed Date:  2010-10-08     Revised Date:  2012-01-19    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  519-24     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
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MeSH Terms
Hypertension / etiology
Pregnancy Complications, Cardiovascular / diagnosis,  physiopathology,  therapy*
Pregnancy Outcome
Severity of Illness Index
Subclavian Artery / physiopathology
Takayasu Arteritis / diagnosis,  physiopathology,  therapy*

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