Document Detail

Pregnancy-Specific Skin Disorders.
MedLine Citation:
PMID:  25405676     Owner:  NLM     Status:  Publisher    
The pregnancy-specific skin disorders are pruritic, inflammatory eruptions. The current classification by Ambros-Rudolph et al. includes four entities: pemphigoid gestationis (PG), polymorphic eruption of pregnancy (PEP), atopic eruption of pregnancy (AEP), and intrahepatic cholestasis of pregnancy (ICP). Although these disorders are all characterized by intense pruritus during pregnancy, they can be distinguished by timing, morphology, histopathology, treatment and potential for fetal complications. Diagnosis is made by clinical presentation, histology, and immunofluorescence. PEP and AEP typically resolve without sequelae; however, PG may lead to prematurity and low birth weight, and ICP is associated with an increased risk of prematurity, fetal distress, and intrauterine fetal demise. The potential for serious fetal complications necessitates a thorough evaluation of pregnancy-related pruritus. This article will discuss the skin disorders specific to pregnancy, with a focus on clinical presentation, potential for fetal complications, pathogenesis, diagnosis, and treatment.
S White; R Philips; M M Neill; E Kelly
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Publication Detail:
Journal Detail:
Title:  Skin therapy letter     Volume:  19     ISSN:  1201-5989     ISO Abbreviation:  Skin Therapy Lett.     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-11-18     Completed Date:  -     Revised Date:  2014-11-19    
Medline Journal Info:
Nlm Unique ID:  9891441     Medline TA:  Skin Therapy Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  7-10     Citation Subset:  -    
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