Document Detail

Pregnancy and Crohn's disease.
MedLine Citation:
PMID:  15711051     Owner:  NLM     Status:  MEDLINE    
Crohn's disease commonly affects women of childbearing age. Available data on Crohn's disease and pregnancy show that women with Crohn's disease can expect to conceive successfully, carry to term and deliver a healthy baby. Control of disease activity before conception and during pregnancy is critical, to optimize both maternal and fetal health. Generally speaking, pharmacological therapy for Crohn's disease during pregnancy is similar to pharmacological therapy for non-pregnant patients. Patients maintained in remission by way of pharmacological therapy should continue it throughout their pregnancy. Most drugs, including sulfasalazine, mesalazine, corticosteroids, and immunosuppressors such as azathioprine and 6-mercaptopurine, are safe, whereas methotrexate is contraindicated.
Christian Mottet; Pascal Juillerat; Jean-Jacques Gonvers; Florian Froehlich; Bernard Burnand; John-Paul Vader; Pierre Michetti; Christian Felley
Publication Detail:
Type:  Journal Article; Review     Date:  2005-02-04
Journal Detail:
Title:  Digestion     Volume:  71     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  2005  
Date Detail:
Created Date:  2005-04-06     Completed Date:  2005-06-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  54-61     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2005 S. Karger AG, Basel.
Division of Gastroenterology and Hepatology, Lausanne University Medical Center, Lausanne, Switzerland.
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MeSH Terms
Anti-Infective Agents / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Crohn Disease* / drug therapy
Drug Therapy, Combination
Glucocorticoids / therapeutic use
Immunologic Factors / therapeutic use
Pregnancy Complications* / drug therapy
Pregnancy Outcome
Reg. No./Substance:
0/Anti-Infective Agents; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Glucocorticoids; 0/Immunologic Factors; 89-57-6/Mesalamine

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