Document Detail


Pregnancies and deliveries in patients with Charcot-Marie-Tooth disease.
MedLine Citation:
PMID:  15699375     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate the effect of maternal Charcot-Marie-Tooth disease (CMT) on pregnancy and delivery. METHODS: Data from the Medical Birth Registry of Norway 1967 to 2002 were surveyed. This registry has compulsory notification of all births. One hundred eight births by mothers with CMT were identified. The reference group consisted of all 2.1 million births by mothers without CMT. RESULTS: Women with CMT had a higher occurrence of presentation anomalies (9.3 vs 4.5%; p = 0.04) and bleeding post partum (12.0 vs 5.8%; p = 0.02). The rate of operative delivery was twice that of the reference group (29.6 vs 15.3%; p = 0.002), and forceps was used three times as often in the CMT group (9.3 vs 2.7; p < 0.001). The majority of CMT cesarean sections were emergency sections. CONCLUSION: Charcot-Marie-Tooth disease increases the risk for complications during delivery, which is linked to a higher occurrence of emergency interventions during birth.
Authors:
Jana Midelfart Hoff; Nils Erik Gilhus; Anne Kjersti Daltveit
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neurology     Volume:  64     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-08     Completed Date:  2005-09-19     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  459-62     Citation Subset:  AIM; IM    
Affiliation:
Section for Neurology, Department of Clinical Medicine, University of Bergen, Bergen, Norway. jana.midelfart.hoff@helse-bergen.no
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MeSH Terms
Descriptor/Qualifier:
Adult
Birth Weight
Cesarean Section / utilization
Charcot-Marie-Tooth Disease / epidemiology*
Delivery, Obstetric / statistics & numerical data*
Emergencies
Female
Gestational Age
Humans
Infant, Newborn
Infant, Premature
Labor Presentation
Male
Norway / epidemiology
Obstetric Labor Complications / epidemiology
Obstetrical Forceps / utilization
Parity
Postoperative Hemorrhage / epidemiology
Pregnancy
Pregnancy Complications / epidemiology*
Pregnancy Outcome
Puerperal Disorders / epidemiology
Retrospective Studies
Risk
Uterine Hemorrhage / epidemiology
Vacuum Extraction, Obstetrical / utilization

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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