| Pregnancies after microsurgical correction of partial epididymal and vasal obstruction. | |
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MedLine Citation:
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PMID: 7657756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A group of 16 infertile patients suspected of having a partial epididymal obstruction on the basis of severe oligozoospermia, normal-sized testes and a normal serum follicle-stimulating hormone, underwent scrotal exploration. Evidence of partial obstruction of the epididymis was found in 13 cases and of the vas deferens in one case, and was supported by finding normal spermatogenesis on testicular biopsy. Vasoepididymostomy or vasovasostomy were performed, resulting in a significant improvement of semen analysis in 50% of cases and in six pregnancies in two patients. The diagnosis of partial epididymal obstruction should be considered when the above criteria are met. If pregnancies do not result when intracytoplasmic sperm injection (ICSI) is used with the ejaculated spermatozoa, a testicular biopsy followed by a microsurgical by-pass procedure should be considered whenever normal spermatogenesis is diagnosed. In all cases, the epididymal spermatozoa should be aspirated during the operation and either used immediately for insemination or stored frozen. The remarkable results of the new artificial reproduction technologies and in particular ICSI, question the indication for microsurgical correction in cases of partial epididymal obstruction. |
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Authors:
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R Hauser; P D Temple-Smith; G J Southwick; J McFarlane; D M de Kretser |
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7565026 - Gamete microsurgery for assisted fertilization. 3718056 - Abnormal axonemes in sperm of fertile men. 7222326 - Vasovasostomy: comparison of two microsurgical techniques. 7480846 - Intracytoplasmic sperm injection (icsi): the brussels experience. 8860106 - Increase in prostaglandin bioavailability precedes the onset of human parturition. 10789266 - Fetal distress. |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Human reproduction (Oxford, England) Volume: 10 ISSN: 0268-1161 ISO Abbreviation: Hum. Reprod. Publication Date: 1995 May |
Date Detail:
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Created Date: 1995-10-02 Completed Date: 1995-10-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8701199 Medline TA: Hum Reprod Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1152-5 Citation Subset: IM |
Affiliation:
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Institute of Reproduction and Development, Monash University, Clayton, Victoria, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Epididymis / surgery* Female Humans Infertility, Male / etiology, pathology, surgery* Male Microsurgery / methods Middle Aged Pregnancy Prognosis Reproductive Techniques* Retrospective Studies Sperm Count Testicular Diseases / pathology, surgery* Vas Deferens / surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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