| Pregestational body mass index, weight gain during pregnancy and maternal hyperglycemia. | |
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MedLine Citation:
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PMID: 20642383 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective. To evaluate the associations between pregestational BMI and weight gain during pregnancy and the risk for maternal hyperglycemia. Methods. The charts of all patients who delivered at our hospital between June 2001 and June 2006 were reviewed. Maternal hyperglycemia categories were defined as GDM (by the Carpenter and Coustan criteria); Impaired glucose tolerance (IGT - only one abnormal value in the 100 g OGTT); Abnormal GCT (≥140 mg/dL) but no high values on the OGTT. Women with GCT < 140 were defined as normal glucose tolerance (NGT). Results. Pregravid BMI and glucose tolerance data were available for 9269 women. We also had data on weight gain during pregnancy for 7766 of these women. There was strong graded association between increasing BMI category and all levels of maternal hyperglycemia. There was significant negative correlation between BMI and weight gain during pregnancy (R = -0.251, P value < 0.0001). However, in the multivariate logistic regression model, only pregestational BMI was significantly associated with maternal hyperglycemia, whereas weight gain during pregnancy was no longer significant. Conclusions. Obesity is a strong predictor for gestational maternal hyperglycemia. Weight gain during pregnancy has less effect. Every effort should be made for pregestational weight reduction in overweight women. |
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Authors:
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Shlomit Riskin-Mashiah; Amit Damti; Grace Younes; Ron Auslander |
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Publication Detail:
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Type: Journal Article Date: 2010-07-20 |
Journal Detail:
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Title: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology Volume: 27 ISSN: 1473-0766 ISO Abbreviation: Gynecol. Endocrinol. Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-06-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8807913 Medline TA: Gynecol Endocrinol Country: England |
Other Details:
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Languages: eng Pagination: 464-7 Citation Subset: IM |
Affiliation:
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Rappaport Faculty of Medicine, Departement of Obstetrics and Gynecology, The Lady Davis Carmel Medical Center, Technion, Haifa, Israel. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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