| Preferential induction of endothelin-1 in a human epidermal equivalent model by narrow-band ultraviolet B light sources. | |
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MedLine Citation:
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PMID: 20584257 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Narrow-band ultraviolet B (NB-UVB; 310-315 nm) is commonly used to treat vitiligo, but the mechanisms underlying the therapeutic effect have not been understood completely. Here, we evaluated the effects of broadband UVB (BB-UVB), NB-UVB, 308 nm xenon chloride (XeCl) excimer laser, and 308 nm XeCl excimer light on the expression of endothelin-1 (ET-1) in a cultured human epidermal tissue model. Our results provide a theoretical basis for the effectiveness of UVB irradiation, including excimer light and excimer laser, in the treatment of vitiligo. |
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Authors:
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Reiko Noborio; Akimichi Morita |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Photodermatology, photoimmunology & photomedicine Volume: 26 ISSN: 1600-0781 ISO Abbreviation: Photodermatol Photoimmunol Photomed Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-29 Completed Date: 2010-10-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9013641 Medline TA: Photodermatol Photoimmunol Photomed Country: Denmark |
Other Details:
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Languages: eng Pagination: 159-61 Citation Subset: IM |
Affiliation:
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Department of Geriatric and Environmental Dermatology, Nagoya City University of Medical Sciences, Nagoya, Japan. noborior@hirakata.kmu.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Endothelin-1
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biosynthesis* Epidermis / metabolism, radiation effects* Humans Ultraviolet Rays* |
| Chemical | |
Reg. No./Substance:
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0/Endothelin-1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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