| Preferential expression of L-type amino acid transporter 1 in ameloblasts during rat tooth development. | |
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MedLine Citation:
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PMID: 15027953 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Certain amino acid transport systems play an important role in supplying organic nutrients to each cell and for cell proliferation during tooth development. However, the mechanisms responsible for such actions are unclear. This study demonstrated for the first time that LAT1 and 4F2hc are expressed during tooth development in prenatal and postnatal rats, and that the transporters show cell-specific expression in ameloblasts, which are the epithelium-derived dental cells. LAT1 and 4F2hc expression was not observed in other dental cells of the developing teeth such as odontoblasts and cementoblasts. Overall, these results suggest that LAT1 and 4F2hc might play an important role in enamel formation. |
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Authors:
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J-C Park; Y B Kim; J H Yoon; H-J Kim; S M Kim; Y Kanai; H Endou; D K Kim |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Anatomia, histologia, embryologia Volume: 33 ISSN: 0340-2096 ISO Abbreviation: Anat Histol Embryol Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-03-18 Completed Date: 2004-06-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7704218 Medline TA: Anat Histol Embryol Country: Germany |
Other Details:
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Languages: eng Pagination: 119-24 Citation Subset: IM |
Affiliation:
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Oral Biology Research Institute, College of Dentistry, Chosun University, 375 Seo-Suk Dong, Dong-ku, Gwang-ju, 501-759, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Ameloblasts
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metabolism* Amino Acid Transport Systems / metabolism Animals Cell Division Immunohistochemistry / veterinary Large Neutral Amino Acid-Transporter 1 / metabolism* Rats Rats, Sprague-Dawley Tooth / cytology, growth & development* |
| Chemical | |
Reg. No./Substance:
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0/Amino Acid Transport Systems; 0/Large Neutral Amino Acid-Transporter 1 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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