Document Detail

Preeclampsia and hypertensive disease in pregnancy: their contributions to cardiovascular risk.
MedLine Citation:
PMID:  22389120     Owner:  NLM     Status:  MEDLINE    
More women than men die each year of cardiovascular disease, which remains the leading cause of death in the United States. Sex-specific factors, including pregnancy-related disorders, should be considered when assessing cardiovascular (CV) risk in women. Hypertensive disorders of pregnancy have been associated with CV risk later in life and may identify women in whom earlier primary prevention may reduce their risk. This article reviews the physiologic changes in blood pressure during pregnancy, current definitions of hypertensive diseases of pregnancy and preeclampsia, and postulated pathophysiologic mechanisms leading to preeclampsia that might contribute to later CV risk. Also summarized are studies providing evidence on the association between hypertensive diseases of pregnancy and future CV risk.
Carolina Valdiviezo; Vesna D Garovic; Pamela Ouyang
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical cardiology     Volume:  35     ISSN:  1932-8737     ISO Abbreviation:  Clin Cardiol     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-05     Completed Date:  2012-07-12     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  160-5     Citation Subset:  IM    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA.
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MeSH Terms
Cardiovascular Diseases / etiology*,  physiopathology
Hypertension, Pregnancy-Induced / etiology*,  physiopathology
Pre-Eclampsia / etiology*,  physiopathology
Risk Factors
Comment In:
Clin Cardiol. 2012 Aug;35(8):518-9; author reply 519   [PMID:  22508504 ]

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