| Predonation hydration and applied muscle tension combine to reduce presyncopal reactions to blood donation. | |
| | |
MedLine Citation:
|
PMID: 20113455 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: A randomized controlled trial was conducted to test the effects of hydration and applied muscle tensing on presyncopal reactions to blood donation. Both interventions are designed to prevent the decreases in blood pressure that can contribute to such reactions, but due to the distinct physiologic mechanisms underlying their pressor responses it was hypothesized that a combined intervention would yield the greatest benefit. STUDY DESIGN AND METHODS: Before blood donation, first- and second-time blood donors (mean age, 20.2 years; SD, 4.9) were randomly assigned to 1) standard donation, 2) placebo (leg exercise before venipuncture), 3) predonation water, or 4) predonation water and leg exercise during donation. RESULTS: Main effects of group were observed for phlebotomist classification of vasovagal reactions (chi(2)(3) = 8.38, p < 0.05) and donor reports of presyncopal reactions (chi(2)(3) = 13.16, p < 0.01). Follow-up analyses of phlebotomist classifications revealed fewer reactions in the predonation water and predonation water and leg exercise groups relative to placebo but not standard donation. Follow-up analyses of self-reported reactions revealed that women, but not men, had lower scores in both the predonation water and the predonation water and leg exercise groups relative to both placebo and standard donation. CONCLUSIONS: Predonation hydration and a combination of hydration and leg exercise may help attenuate presyncopal reactions in relatively novice donors, although future studies with larger samples are required to confirm this effect. |
| | |
Authors:
|
Christopher R France; Blaine Ditto; Mary Ellen Wissel; Janis L France; Tara Dickert; Aaron Rader; Kadian Sinclair; Sarah McGlone; Zina Trost; Erin Matson |
Related Documents
:
|
1941645 - Musculoskeletal responses of spinal cord injured individuals to functional neuromuscula... 1886485 - Physiological responses to wrist weights during endurance cycling in normal subjects. 20558755 - Roles of nitric oxide synthase and cyclooxygenase in leg vasodilation and oxygen consum... 161225 - The effect of unilateral isokinetic strength training on local adipose and muscle tissu... 17214405 - Yohimbine: the effects on body composition and exercise performance in soccer players. 21932695 - Chest physiotherapy and breathing exercises for cardiac surgery patients in sweden--a n... |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural Date: 2010-01-22 |
Journal Detail:
|
Title: Transfusion Volume: 50 ISSN: 1537-2995 ISO Abbreviation: Transfusion Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-07-05 Completed Date: 2010-07-19 Revised Date: 2011-09-12 |
Medline Journal Info:
|
Nlm Unique ID: 0417360 Medline TA: Transfusion Country: United States |
Other Details:
|
Languages: eng Pagination: 1257-64 Citation Subset: IM |
Affiliation:
|
Ohio University, Athens, Ohio 45701, USA. france@ohio.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Blood Donors* Blood Pressure* Exercise* Female Follow-Up Studies Humans Male Sex Factors Syncope / etiology, prevention & control* Water / administration & dosage* |
| Grant Support | |
ID/Acronym/Agency:
|
HL077438/HL/NHLBI NIH HHS; R01 HL077438-04/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
7732-18-5/Water |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Blood transfusions increase cerebral, splanchnic, and renal oxygenation in anemic preterm infants.
Next Document: Analysis of sample-to-cutoff ratios on chemiluminescent immunoassays used for blood donor screening ...