| Predominant breast-feeding from birth to six months is associated with fewer gastrointestinal infections and increased risk for iron deficiency among infants. | |
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MedLine Citation:
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PMID: 18641197 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Iron deficiency (ID) is prevalent among infants world-wide and may be more likely among infants born to women living in disadvantaged environments. A strategy to address ID in this context is to feed iron-fortified formula, but this may create risk for gastrointestinal (GI) infection. Our objective was to investigate the relationship between infant feeding practices, iron status, and likelihood of a GI infection in the first 6 mo of life. We conducted a prospective study at a public hospital in Guadalajara, Mexico. Healthy women who gave birth to a healthy term infant were eligible to participate. Each month, mothers (n = 154) provided information on infant feeding methods and symptoms of GI infection. At 6 mo of age, infants' iron status was assessed [hemoglobin (Hb) and serum ferritin concentration]. When compared with nonpredominantly breast-fed [partially breast-feeding (PBF) and formula feeding (FF) combined], predominantly breast-fed (PRBF) infants to 6 mo had a lower incidence of GI infection from 0-6 mo [18 vs. 33%; P = 0.04; adjusted odds ratio (OR) = 0.4; 95% CI = 0.2, 1.0] but a higher risk for ID (serum ferritin < 12 microg/L) at 6 mo (22 vs. 4%; P = 0.001; adjusted OR = 9.2; 95% CI = 2.3, 37.0). Anemia (Hb < 110 g/L) prevalence did not differ among feeding groups (13% for PRBF, 19% for PBF, and 4% for FF; P = 0.09). In this low-income population, our results suggest that PRBF should be promoted and the risk for ID managed using public health and nutrition strategies. |
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Authors:
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Eva C Monterrosa; Edward A Frongillo; Edgar M Vásquez-Garibay; Enrique Romero-Velarde; Linda M Casey; Noreen D Willows |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of nutrition Volume: 138 ISSN: 1541-6100 ISO Abbreviation: J. Nutr. Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-07-21 Completed Date: 2008-09-02 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0404243 Medline TA: J Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 1499-504 Citation Subset: IM |
Affiliation:
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Department of Agricultural, Food, and Nutritional Sciences, University of Alberta, T6G 2P5 Edmonton, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia, Iron-Deficiency / epidemiology, etiology*, prevention & control Breast Feeding* / adverse effects Female Gastrointestinal Diseases / prevention & control* Humans Infant Infant Formula / chemistry Infant Nutritional Physiological Phenomena Infant, Newborn Iron, Dietary / administration & dosage Male Mexico / epidemiology Poverty Prospective Studies Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Iron, Dietary |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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