|Predictors of weight loss during radiation therapy.|
|PMID: 11743469 Owner: NLM Status: MEDLINE|
|OBJECTIVE: To define risk factors for weight loss or dehydration during radiation therapy (RT). STUDY DESIGN AND SETTING: Retrospective chart review, academic tertiary care center. RESULTS: The incidence of severe weight loss during RT was 32.7%, the incidence of dehydration was 10.9%, and the rate of prophylactic feeding gastrostomy tube placement was 32%. The patients most likely to suffer severe weight loss included patients with tumor sites of nasopharynx and base of tongue, those treated with chemoradiation, and patients with severe pretreatment weight loss. Prophylactic feeding gastrostomy tube placement before RT significantly reduced the incidence of severe weight loss and hospitalization during RT. CONCLUSION: Severe weight loss and dehydration during RT for head and neck cancer is common. Prophylactic feeding gastrostomy tubes significantly reduce the incidence of severe weight loss and hospitalization for dehydration during RT when placed before onset of RT. Patients at risk for severe weight loss include those with severe pretreatment weight loss, tumors of the nasopharynx and base of tongue, or treatment with chemoradiation.|
|M E Beaver; K E Matheny; D B Roberts; J N Myers|
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|Type: Journal Article|
|Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: 125 ISSN: 0194-5998 ISO Abbreviation: Otolaryngol Head Neck Surg Publication Date: 2001 Dec|
|Created Date: 2001-12-14 Completed Date: 2002-01-25 Revised Date: 2004-11-17|
Medline Journal Info:
|Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: United States|
|Languages: eng Pagination: 645-8 Citation Subset: IM|
|Texas Voice Center, TX, USA.|
|APA/MLA Format Download EndNote Download BibTex|
Enteral Nutrition / statistics & numerical data
Gastrostomy / statistics & numerical data
Head and Neck Neoplasms / radiotherapy*
Hospitalization / statistics & numerical data
Laryngeal Neoplasms / radiotherapy*
Nasopharyngeal Neoplasms / radiotherapy*
Pharyngeal Neoplasms / radiotherapy*
Predictive Value of Tests
Radiotherapy / adverse effects*
Severity of Illness Index
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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