| Predictors of weight loss during radiation therapy. | |
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MedLine Citation:
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PMID: 11743469 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To define risk factors for weight loss or dehydration during radiation therapy (RT). STUDY DESIGN AND SETTING: Retrospective chart review, academic tertiary care center. RESULTS: The incidence of severe weight loss during RT was 32.7%, the incidence of dehydration was 10.9%, and the rate of prophylactic feeding gastrostomy tube placement was 32%. The patients most likely to suffer severe weight loss included patients with tumor sites of nasopharynx and base of tongue, those treated with chemoradiation, and patients with severe pretreatment weight loss. Prophylactic feeding gastrostomy tube placement before RT significantly reduced the incidence of severe weight loss and hospitalization during RT. CONCLUSION: Severe weight loss and dehydration during RT for head and neck cancer is common. Prophylactic feeding gastrostomy tubes significantly reduce the incidence of severe weight loss and hospitalization for dehydration during RT when placed before onset of RT. Patients at risk for severe weight loss include those with severe pretreatment weight loss, tumors of the nasopharynx and base of tongue, or treatment with chemoradiation. |
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Authors:
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M E Beaver; K E Matheny; D B Roberts; J N Myers |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: 125 ISSN: 0194-5998 ISO Abbreviation: Otolaryngol Head Neck Surg Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2001-12-14 Completed Date: 2002-01-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: United States |
Other Details:
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Languages: eng Pagination: 645-8 Citation Subset: IM |
Affiliation:
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Texas Voice Center, TX, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dehydration
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classification,
epidemiology,
etiology*,
therapy Enteral Nutrition / statistics & numerical data Female Gastrostomy / statistics & numerical data Glottis* Head and Neck Neoplasms / radiotherapy* Hospitalization / statistics & numerical data Humans Hypopharynx* Incidence Laryngeal Neoplasms / radiotherapy* Male Middle Aged Nasopharyngeal Neoplasms / radiotherapy* Oropharynx* Patient Selection Pharyngeal Neoplasms / radiotherapy* Predictive Value of Tests Radiotherapy / adverse effects* Retrospective Studies Risk Factors Severity of Illness Index Weight Loss* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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