Document Detail

Predictors of very late recurrence of atrial fibrillation after circumferential pulmonary vein ablation.
MedLine Citation:
PMID:  18855350     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Early recurrence of atrial fibrillation (ERAF) after catheter ablation is common and has been thoroughly studied. However, very late recurrence of atrial fibrillation (VLRAF) is rarely researched, and its characteristics have not been determined. HYPOTHESIS: The aim of this study was to investigate the clinical characteristics of VLRAF after circumferential pulmonary vein ablation (CPVA), and to identify the risk factors for VLRAF. METHODS: We retrospectively studied 259 consecutive patients with atrial fibrillation (AF) who were referred for CPVA. Clinical variables were investigated and predictors of VLRAF were identified. RESULTS: A total of 249 patients were enrolled in this study. After a mean follow-up of 18.2 +/- 4.4 mo, 14 patients (5.6%) had VLRAF. Patients with VLRAF were more likely than those without recurrence to have ERAF (78.6% versus 17.8%, p = 0.000) and persistent AF (50.0% versus 13.0%, p = 0.000), but were less likely to achieve pulmonary vein (PV) isolation (78.6% versus 97.6%, p = 0.000). Bivariate analysis demonstrated that ERAF (odds ratio [OR] 8.148, 95% confidence interval [CI] 2.197-30.222; p = 0.002), persistent AF (OR 8.853, 95% CI 1.773-16.155; p = 0.003), and lack of PV isolation (OR 7.530, 95% CI 1.792-33.122; p = 0.006) were related to VLRAF. Multivariate logistic regression analysis only identified ERAF as a predictor of VLRAF after CPVA (OR 7.461, 95% CI 1.696-24.836; p = 0.006). CONCLUSIONS: Very late recurrence of AF is uncommon after CPVA. That occurs more commonly in patients with ERAF.
Hailong Tao; Xingpeng Liu; Jianzeng Dong; Deyong Long; Ribo Tang; Bin Zheng; Junping Kang; Ronghui Yu; Ying Tian; Changsheng Ma
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  31     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-21     Completed Date:  2009-01-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  463-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2008 Wiley Periodicals, Inc.
Department of Cardiology, Beijing AnZhen Hospital, Capital Medical University, Beijing, China.
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MeSH Terms
Aged, 80 and over
Atrial Fibrillation / physiopathology,  surgery*,  ultrasonography
Catheter Ablation / methods*
Follow-Up Studies
Heart Conduction System / surgery*
Heart Rate / physiology
Middle Aged
Pulmonary Veins / innervation,  surgery*
Retrospective Studies
Time Factors
Treatment Outcome
Young Adult
Erratum In:
Clin Cardiol. 2008 Nov;31(11):559
Note: Tao, Hailong [added]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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