| Predictors of renal involvement in patients with systemic lupus erythematosus. | |
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MedLine Citation:
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PMID: 17891918 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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From a cohort of 109 patients (105 females and 4 males) treated for systemic lupus erythematosus (SLE), 20 patients (18.3%) developed new episodes of lupus nephritis and 89 patients (81.7%) remained free of renal involvement during the follow-up period. The mean duration of follow up was 39.1 +/- 54.4 months. Clinical characteristics associated with developing lupus nephritis were a high systolic blood pressure (> or = 130 mmHg), photosensitivity, cutaneous vasculitis and gastrointestinal (GI) symptoms. Laboratory abnormalities associated with the development of lupus nephritis were hemoglobin < 10 mg/dl, hematocrit < 30%, blood urea nitrogen > 12 mg/dl, serum creatinine > 1.3 mg/dl, ESR > 60, the third component of complement (C3) level < 0.45 and positive antidsDNA antibody. After a multivariable analysis, only high systolic blood pressure, cutaneous vasculitis, hemoglobin < 10 mg/dl and serum creatinine > 1.3 mg/dl remained as statistically significant risk factors for developing lupus nephritis. |
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Authors:
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Bancha Satirapoj; Jeerapat Wongchinsri; Nantana Youngprang; Boonraksa Laonapaporn; Thongdee Chitrada; Sumonkarn Lapkittichareonchai; Jayanton Patumanon |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand Volume: 25 ISSN: 0125-877X ISO Abbreviation: Asian Pac. J. Allergy Immunol. Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-09-25 Completed Date: 2007-11-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8402034 Medline TA: Asian Pac J Allergy Immunol Country: Thailand |
Other Details:
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Languages: eng Pagination: 17-25 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Nopparat Rajathanee Hospital, Thailand. satirapoj@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Antinuclear / blood Cohort Studies Female Humans Hypertension / physiopathology Kidney / physiopathology Lupus Erythematosus, Systemic / complications, immunology, physiopathology* Lupus Nephritis / etiology*, immunology, physiopathology Male Middle Aged Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Antinuclear |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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