Document Detail

Predictors of preterm birth.
MedLine Citation:
PMID:  16730012     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This is a systematic review to assess published scientific evidence on preterm birth predictors. METHODS: An Internet search for predictors of preterm birth was performed and the evidence level of each method was evaluated. RESULTS: There is strong evidence that preterm birth can be predicted using vaginal sonography to evaluate cervical characteristics, fetal fibronectin in cervicovaginal secretions and interleukin-6 in amniotic fluid. There is consistent evidence that digital cervical examination is a weak predictor, and controversy regarding home uterine activity monitoring. There is scanty evidence about the predictive ability of maternal history and perceptions of symptoms since the study design fails to provide high evidence level. CONCLUSION: Cervical evaluation by vaginal sonography, fetal fibronectin and interleukin-6 are the best methods for predicting preterm birth.
F G Krupa; D Faltin; J G Cecatti; F G C Surita; J P Souza
Publication Detail:
Type:  Journal Article; Review     Date:  2006-05-24
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  94     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-04     Completed Date:  2006-11-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  5-11     Citation Subset:  IM    
Department of Obstetrics and Gynecology University of Campinas, Campinas, SP, Brazil.
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MeSH Terms
Amniotic Fluid / chemistry*
Fetus / chemistry*
Fibronectins / analysis*
Infant, Newborn
Interleukin-6 / analysis*
Magnetic Resonance Imaging
Monitoring, Ambulatory
Predictive Value of Tests
Premature Birth* / blood
Ultrasonography, Prenatal
Uterine Contraction / physiology
Uterus / physiology
Vagina / ultrasonography
Reg. No./Substance:
0/Fibronectins; 0/Interleukin-6

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