|Predictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility.|
|PMID: 22270557 Owner: NLM Status: MEDLINE|
|OBJECTIVE: To identify risk factors for pregnancy outcomes in couples treated with intracervical or intrauterine insemination, with or without superovulation for unexplained or male-factor infertility.
DESIGN: Secondary analysis of data from a randomized superovulation and intrauterine insemination trial.
SETTING: Academic medical centers.
INTERVENTION(S): Treatment continued for four cycles unless pregnancy was achieved.
PATIENT(S): Out of 932 couples randomized to four treatment groups, 664 couples who had completed the lifestyle questionnaires were assessed for occurrence of pregnancy and live birth.
MAIN OUTCOME MEASURE(S): Pregnancy and live birth.
RESULT(S): The pregnancy and live birth rates were significantly higher in couples in which the female partners reported that they had consumed coffee or tea in the past or drank alcoholic beverages in the past (past users) compared with those who had never consumed coffee, tea, or alcoholic beverages. Past users also had significantly higher pregnancy and live birth rates than those currently consuming coffee or tea or alcoholic beverages. Demographic, occupational exposure, and other lifestyle factors were not significant.
CONCLUSION(S): Couples in which the female partners drank coffee, tea, or alcoholic beverages in the past had higher pregnancy and live birth rates compared with never or current users. When discontinuing these habits, they might have made other lifestyle changes to improve the pregnancy outcome.
|Hao Huang; Karl R Hansen; Pamela Factor-Litvak; Sandra A Carson; David S Guzick; Nanette Santoro; Michael P Diamond; Esther Eisenberg; Heping Zhang;|
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|Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural Date: 2012-01-23|
|Title: Fertility and sterility Volume: 97 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2012 Apr|
|Created Date: 2012-04-02 Completed Date: 2012-05-30 Revised Date: 2013-04-03|
Medline Journal Info:
|Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States|
|Languages: eng Pagination: 959-67 Citation Subset: IM|
|Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.|
|Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA.|
|APA/MLA Format Download EndNote Download BibTex|
Academic Medical Centers
Alcohol Drinking / adverse effects
Alcoholic Beverages / adverse effects
Coffee / adverse effects
Infertility / etiology, physiopathology, therapy*
Infertility, Male / epidemiology, physiopathology, therapy*
Insemination, Artificial* / adverse effects
Ovulation Induction* / adverse effects
Risk Reduction Behavior
Tea / adverse effects
|HD55925/HD/NICHD NIH HHS; U10 HD039005-10/HD/NICHD NIH HHS; U10 HD055925-05/HD/NICHD NIH HHS; U10 HD39005/HD/NICHD NIH HHS; UL1 TR000064/TR/NCATS NIH HHS|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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