| Predictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility. | |
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MedLine Citation:
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PMID: 22270557 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To identify risk factors for pregnancy outcomes in couples treated with intracervical or intrauterine insemination, with or without superovulation for unexplained or male-factor infertility. DESIGN: Secondary analysis of data from a randomized superovulation and intrauterine insemination trial. SETTING: Academic medical centers. INTERVENTION(S): Treatment continued for four cycles unless pregnancy was achieved. PATIENT(S): Out of 932 couples randomized to four treatment groups, 664 couples who had completed the lifestyle questionnaires were assessed for occurrence of pregnancy and live birth. MAIN OUTCOME MEASURE(S): Pregnancy and live birth. RESULT(S): The pregnancy and live birth rates were significantly higher in couples in which the female partners reported that they had consumed coffee or tea in the past or drank alcoholic beverages in the past (past users) compared with those who had never consumed coffee, tea, or alcoholic beverages. Past users also had significantly higher pregnancy and live birth rates than those currently consuming coffee or tea or alcoholic beverages. Demographic, occupational exposure, and other lifestyle factors were not significant. CONCLUSION(S): Couples in which the female partners drank coffee, tea, or alcoholic beverages in the past had higher pregnancy and live birth rates compared with never or current users. When discontinuing these habits, they might have made other lifestyle changes to improve the pregnancy outcome. |
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Authors:
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Hao Huang; Karl R Hansen; Pamela Factor-Litvak; Sandra A Carson; David S Guzick; Nanette Santoro; Michael P Diamond; Esther Eisenberg; Heping Zhang; |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural Date: 2012-01-23 |
Journal Detail:
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Title: Fertility and sterility Volume: 97 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-04-02 Completed Date: 2012-05-30 Revised Date: 2013-04-03 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 959-67 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Academic Medical Centers Adult Alcohol Drinking / adverse effects Alcoholic Beverages / adverse effects Chi-Square Distribution Coffee / adverse effects Female Humans Infertility / etiology, physiopathology, therapy* Infertility, Male / epidemiology, physiopathology, therapy* Insemination, Artificial* / adverse effects Life Style* Live Birth* Logistic Models Male Middle Aged Multivariate Analysis Ovulation Induction* / adverse effects Pregnancy Pregnancy Rate* Prospective Studies Questionnaires Risk Assessment Risk Factors Risk Reduction Behavior Superovulation Tea / adverse effects Treatment Outcome United States Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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HD55925/HD/NICHD NIH HHS; U10 HD039005-10/HD/NICHD NIH HHS; U10 HD055925-05/HD/NICHD NIH HHS; U10 HD39005/HD/NICHD NIH HHS; UL1 TR000064/TR/NCATS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Coffee; 0/Tea |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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