Document Detail


Predictors of pregnancy and live birth after insemination in couples with unexplained or male-factor infertility.
MedLine Citation:
PMID:  22270557     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To identify risk factors for pregnancy outcomes in couples treated with intracervical or intrauterine insemination, with or without superovulation for unexplained or male-factor infertility.
DESIGN: Secondary analysis of data from a randomized superovulation and intrauterine insemination trial.
SETTING: Academic medical centers.
INTERVENTION(S): Treatment continued for four cycles unless pregnancy was achieved.
PATIENT(S): Out of 932 couples randomized to four treatment groups, 664 couples who had completed the lifestyle questionnaires were assessed for occurrence of pregnancy and live birth.
MAIN OUTCOME MEASURE(S): Pregnancy and live birth.
RESULT(S): The pregnancy and live birth rates were significantly higher in couples in which the female partners reported that they had consumed coffee or tea in the past or drank alcoholic beverages in the past (past users) compared with those who had never consumed coffee, tea, or alcoholic beverages. Past users also had significantly higher pregnancy and live birth rates than those currently consuming coffee or tea or alcoholic beverages. Demographic, occupational exposure, and other lifestyle factors were not significant.
CONCLUSION(S): Couples in which the female partners drank coffee, tea, or alcoholic beverages in the past had higher pregnancy and live birth rates compared with never or current users. When discontinuing these habits, they might have made other lifestyle changes to improve the pregnancy outcome.
Authors:
Hao Huang; Karl R Hansen; Pamela Factor-Litvak; Sandra A Carson; David S Guzick; Nanette Santoro; Michael P Diamond; Esther Eisenberg; Heping Zhang;
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural     Date:  2012-01-23
Journal Detail:
Title:  Fertility and sterility     Volume:  97     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-04-02     Completed Date:  2012-05-30     Revised Date:  2014-05-02    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  959-67     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Academic Medical Centers
Adult
Alcohol Drinking / adverse effects
Alcoholic Beverages / adverse effects
Chi-Square Distribution
Coffee / adverse effects
Female
Humans
Infertility / etiology,  physiopathology,  therapy*
Infertility, Male / epidemiology,  physiopathology,  therapy*
Insemination, Artificial* / adverse effects
Life Style*
Live Birth*
Logistic Models
Male
Middle Aged
Multivariate Analysis
Ovulation Induction* / adverse effects
Pregnancy
Pregnancy Rate*
Prospective Studies
Questionnaires
Risk Assessment
Risk Factors
Risk Reduction Behavior
Superovulation
Tea / adverse effects
Treatment Outcome
United States
Young Adult
Grant Support
ID/Acronym/Agency:
HD55925/HD/NICHD NIH HHS; U10 HD039005/HD/NICHD NIH HHS; U10 HD039005-10/HD/NICHD NIH HHS; U10 HD055925-05/HD/NICHD NIH HHS; U10 HD055936/HD/NICHD NIH HHS; U10 HD39005/HD/NICHD NIH HHS; UL1 TR000064/TR/NCATS NIH HHS
Chemical
Reg. No./Substance:
0/Coffee; 0/Tea
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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