| Predictors of outcome in prophylactic lithium treatment: a 2-year prospective study. | |
MedLine Citation:
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PMID: 2140378 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose of this study of 133 affective disorder patients consecutively referred to start prophylactic lithium treatment was to identify informative predictors of outcome. Non-adherence to treatment was mainly predicted by substance abuse and many earlier admissions. Non-response among the 78 patients adhering to lithium treatment was mainly predicted by female sex, young age and previously chronic course. The overall response rate was rather poor and an excess mortality rate was found. It is suggested that patients with substance abuse should not be offered prophylactic lithium treatment unless intensive control and support is practicable, and patients with a chronic course need a more effective treatment than lithium can offer. |
Authors:
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J Aagaard; P Vestergaard |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of affective disorders Volume: 18 ISSN: 0165-0327 ISO Abbreviation: J Affect Disord Publication Date: 1990 Apr |
Date Detail:
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Created Date: 1990-06-27 Completed Date: 1990-06-27 Revised Date: 2009-09-28 |
Medline Journal Info:
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Nlm Unique ID: 7906073 Medline TA: J Affect Disord Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 259-66 Citation Subset: IM |
Affiliation:
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Clinical Department A, Institute of Psychiatric Demography, Aarhus Psychiatric Hospital, Risskov, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bipolar Disorder / prevention & control*, psychology Female Follow-Up Studies Humans Lithium / administration & dosage* Male Middle Aged Patient Admission Patient Compliance* Risk Factors |
| Chemical | |
Reg. No./Substance:
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7439-93-2/Lithium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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