Document Detail

Predictors of mortality in neonatal septicemia in an underresourced setting.
MedLine Citation:
PMID:  21053706     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the predictors of mortality in neonatal septicemia.
METHOD: The records of babies with culture-proven septicemia managed in a Nigerian newborn unit between 2006 and 2008 were studied using bivariate and multivariate analysis.
RESULTS: Out of 174 babies with septicemia, 56 (32.2%) died. Outborn babies, babies with estimated gestational age (EGA) less than 32 weeks, weight less than 1.5 kg, temperature less than 38 degrees C, respiratory distress, abdominal distension, poor skin color, hypoglycemia, and infection with gram-negative pathogens were significantly associated with death by bivariate analysis. Multivariate analysis of these risk factors confirmed that EGA less than 32 weeks (odds ratio [OR], 5.5), respiratory distress (OR, 3.4), abdominal distension (OR, 2.7), poor skin color (OR, 3.3), and hypoglycemia (OR, 5.2) had significant independent contributions to the occurrence of death among babies with culture-proven septicemia.
CONCLUSION: Most of the identified predictors of mortality are modifiable and can be used to draw up a screening tool to determine the clinical severity among septic babies.
Tinuade A Ogunlesi; Olusoga B Ogunfowora
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  102     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-08     Completed Date:  2010-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  915-21     Citation Subset:  IM    
Department of Pediatrics, Olabisi Onabanjo University, Sagamu, Nigeria.
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MeSH Terms
Infant, Newborn
Infant, Newborn, Diseases / mortality
Infant, Premature
Infant, Premature, Diseases / mortality
Nigeria / epidemiology
Sepsis / mortality*

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