| Predictors of left ventricular recovery in a cohort of peripartum cardiomyopathy patients recruited via the internet. | |
| | |
MedLine Citation:
|
PMID: 20863583 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
BACKGROUND: Peripartum cardiomyopathy (PPCM) is the onset of acute heart failure without demonstrable cause during the last month of pregnancy or within five months after delivery. The purpose of this study was to create a prospective registry of PPCM patients with the assistance of the internet and identify clinical factors predictive of ejection fraction (EF) recovery. METHODS: Patients with PPCM were identified by novel web-based methods. Subjects were categorized as recovered (EF>50) or nonrecovered (EF<50) and compared on the basis of demographic and clinical variables. RESULTS: Fifty-five subjects met criteria for inclusion. There was a statistically significant association between diagnosis during third trimester and persistent systolic dysfunction (25% vs. 4.7%, p=0.03). Gestational hypertension and breastfeeding were significantly associated with EF recovery (48.8% vs. 16.7%, p=0.046, and 39.5% vs. 8.3%, p=0.04, respectively). EF normalization occurred in all patients with EF(1)≥35%. CONCLUSIONS: Presence of gHTN, EF≥35% at diagnosis, breastfeeding, and postpartum diagnosis were all significantly associated with recovery of systolic function. Internet recruitment may be a valuable tool for studying PPCM. |
| | |
Authors:
|
Jordan G Safirstein; Angela S Ro; Sreeram Grandhi; Lin Wang; James D Fett; Cezar Staniloae |
Related Documents
:
|
7193403 - Evaluation of m-mode echographic estimates of left ventricle function: relationship of ... 790933 - New evidence for inferoposterior myocardial infarction on surface potential maps. 17674083 - Etiology, management, and outcome of pediatric pericardial effusions. |
Publication Detail:
|
Type: Journal Article Date: 2010-09-21 |
Journal Detail:
|
Title: International journal of cardiology Volume: 154 ISSN: 1874-1754 ISO Abbreviation: Int. J. Cardiol. Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2011-12-05 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 27-31 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Cardiology, The Gagnon Cardiovascular Institute at Morristown Memorial Hospital, Morristown, NJ, United States. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Plasma osteopontin reveals left ventricular reverse remodelling following cardiac resynchronization ...
Next Document: Estimating the value of social care.