Document Detail


Predictors of isotonic exercise in patients with heart failure.
MedLine Citation:
PMID:  11445754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Study aims were to determine the predictors of isotonic resistance exercise performance in patients with advanced heart failure and to compare the preexercise values of patients who experienced a negative physiologic response to resistance exercise with those who had minimal or no response. METHODS: A correlational design was used. After pharmacologic left ventricular unloading therapy using a pulmonary artery catheter, 34 patients with advanced heart failure performed graduated isotonic weight-lifting exercises. Measurements were made of hemodynamics and rating of perceived exertion after each test. RESULTS: The following variables, measured at baseline, were significantly correlated with the amount of weight patients were able to lift: rating of perceived exertion (RPE; r = -0.42, P = 0.014); diastolic blood pressure (DBP; r = 0.49, P = 0.03); systolic blood pressure (SBP; r = 0.40, P = 0.017); pulmonary capillary wedge pressure (PCWP; r = 0.39, P = 0.026); and right atrial pressure (RAP; r = 0.35, P = 0.041). Multiple regression analysis, using a stepwise procedure, showed that 47% of the variance in exercise performance was explained by DBP, RPE, and PCWP. There were no significant differences in baseline hemodynamics, ejection fraction, or age between the group of patients who had a negative hemodynamic response at peak exercise and the group of patients who had minimal or no response. CONCLUSIONS: Resting PCWP, DBP, and RPE can provide important information to help clinicians predict isotonic resistance exercise performance in patients with advanced heart failure. However, those patients who have a negative response to this type of exercise cannot be distinguished at baseline by clinical characteristics or age.
Authors:
M L King; K A Dracup; M A Woo
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  33     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-10     Completed Date:  2001-12-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1090-5     Citation Subset:  IM; S    
Affiliation:
UCLA School of Nursing and Medicine and Ahmanson-UCLA Cardiomyopathy Center, University of California at Los Angeles, USA. Mlking@nmscd.med.navy.mil
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Atrial Function, Right
Blood Pressure
Catheterization, Swan-Ganz
Exercise Tolerance*
Female
Heart Failure / physiopathology*
Heart Rate
Hemodynamics*
Humans
Isotonic Contraction*
Male
Middle Aged
Physical Exertion
Predictive Value of Tests
Pulmonary Wedge Pressure
Statistics as Topic
Weight Lifting

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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