| Predictors of increased left ventricular filling pressure in dialysis patients with preserved left ventricular ejection fraction. | |
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MedLine Citation:
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PMID: 20017222 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To study the left and right ventricular function and to assess the predictors of increased left ventricular (LV) filling pressure in dialysis patients with preserved LV ejection fraction. METHODS: This study included 63 consecutive patients (age 57+/-14 years, 57% women) with end-stage renal failure. Echocardiography, including tissue Doppler measurements, was performed in all patients. Based on the median value of the ratio of transmitral early diastolic velocity to early myocardial velocity (E/E' ratio), patients were divided into 2 groups: the group with high filling pressure (E/E'>10.16) and the group with low filling pressure (E/E'< or =10.16). RESULTS: Compared with patients with low filling pressure, the group of patients with high filling pressure included a higher proportion of diabetic patients (41% vs 13%, P=0.022) and had greater LV mass index (211+/-77 vs 172+/-71 g/m3, P=0.04), lower LV lateral long axis amplitude (1.4+/-0.3 vs 1.6+/-0.3 cm, P=0.01), lower E wave (84+/-19 vs 64+/-18cm/s, P<0.001), higher systolic myocardial velocity (S': 8.6+/-1. 5 vs 7.0+/-1.3 cm/s, P<0.001), and lower diastolic myocardial velocities (E': 6.3+/-1.9 vs 9.5+/-2.9 cm/s, P<0.001; A': 8.4+/-1.9 vs 9.7+/-2.5 cm/s, P=0.018). Multivariate analysis identified LV systolic myocardial velocity - S' wave (adjusted odds ratio, 1.909; 95% confidence interval, 1.060-3.439; P=0.031) and age (1.053; 1.001-1.108; P=0.048) as the only independent predictors of high LV filling pressure in dialysis patients. CONCLUSIONS: In dialysis patients with preserved left ventricular ejection fraction, reduced systolic myocardial velocity and elderly age are independent predictors of increased left ventricular filling pressure. |
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Authors:
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Gani Bajraktari; Mimoza Berbatovci-Ukimeraj; Ali Hajdari; Lavdim Ibraimi; Irfan Daullxhiu; Ymer Elezi; Gjin Ndrepepa |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Croatian medical journal Volume: 50 ISSN: 1332-8166 ISO Abbreviation: Croat. Med. J. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-17 Completed Date: 2010-02-24 Revised Date: 2010-09-28 |
Medline Journal Info:
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Nlm Unique ID: 9424324 Medline TA: Croat Med J Country: Croatia |
Other Details:
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Languages: eng Pagination: 543-9 Citation Subset: IM |
Affiliation:
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Service of Cardiology, Clinic of Internal Medicine, University Clinical Centre of Kosova, Rrethi i Spitalit, p.n. 10000 Prishtina, Kosovo. ganibajraktari@yahoo.co.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Echocardiography Female Heart Failure / physiopathology Heart Ventricles / physiopathology* Humans Kidney Failure, Chronic / physiopathology*, therapy Male Middle Aged Prognosis Renal Dialysis* Stroke Volume / physiology* Ventricular Function, Left / physiology* Ventricular Pressure / physiology* |
| Comments/Corrections | |
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