Document Detail


Predictors of in-hospital outcome after primary percutaneous coronary intervention for recurrent myocardial infarction.
MedLine Citation:
PMID:  18654004     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Recurrent acute myocardial infarction (AMI) is a deteriorated condition with high in-hospital morbidity and mortality, but the predictors of in-hospital outcome after primary percutaneous coronary intervention (PCI) for repeat AMI remain unclear. METHODS AND RESULTS: Using the AMI-Kyoto Multi-Center Risk Study database, clinical background, angiographic findings, results of primary PCI, and in-hospital prognosis were retrospectively compared between primary PCI-treated AMI patients with previous myocardial infarction (MI) (repeat-MI patients, n=235) and those without previous MI (first-MI patients, n=1,550). The repeat-MI patients had higher prevalence of Killip class>or=3 at admission, larger number of diseased vessels, and a significantly higher in-hospital mortality rate than the first-MI patients. On multivariate analysis, number of diseased vessels>or=2 or diseased left main trunk (LMT) on initial coronary angiography was the independent positive predictor of in-hospital mortality in the repeat-MI patients, not in the first-MI patients, whereas acquisition of Thrombolysis In Myocardial Infarction 3 flow in the infarct-related artery immediately after primary PCI and elapsed time<24 h were the negative predictors in the first-MI patients, not in the repeat-MI patients. CONCLUSIONS: Number of diseased vessels>or=2 or diseased LMT on initial coronary angiography is an independent risk factor of in-hospital death in recurrent-AMI patients undergoing primary PCI.
Authors:
Jun Shiraishi; Yoshio Kohno; Takahisa Sawada; Mitsuo Takeda; Masayasu Arihara; Masayuki Hyogo; Takakazu Yagi; Takatomo Shima; Takashi Okada; Takeshi Nakamura; Satoaki Matoba; Hiroyuki Yamada; Takeshi Shirayama; Makoto Kitamura; Keizo Furukawa; Hiroaki Matsubara;
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  72     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-25     Completed Date:  2008-10-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1225-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Kyoto First Red Cross Hospital, and Department of Cardiology and Vascular Regenerative Medicine, Kyhoto Prefectural University School of Medicine, Kyoto, Japan. sjun@msj.biglobe.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Angioplasty, Transluminal, Percutaneous Coronary* / adverse effects
Coronary Angiography
Coronary Artery Disease / complications*,  mortality,  physiopathology,  radiography,  therapy
Coronary Circulation
Databases, Factual
Female
Hospital Mortality
Humans
Japan
Male
Middle Aged
Myocardial Infarction / etiology,  mortality,  physiopathology,  radiography,  therapy*
Recurrence
Retrospective Studies
Risk Factors
Severity of Illness Index
Time Factors
Treatment Outcome
Investigator
Investigator/Affiliation:
K Matsubara / ; M Shima / ; M Kiyama / ; H Miyanaga / ; T Nakagawa / ; H Matsui / ; T Kawa / ; Y Kunieda / ; H Fujita / ; T Tanaka / ; K Inoue / ; A Matsuo / ; S Yamaguchi / ; C Yamada / ; Y Oda / ; S Tanabe / ; T Tatsumi / ; N Keira / ; T Nomura / ; K Shiga / ; Y Kohno / ; M Satoda / ; Y Adachi / ; T Kuriyama / ; R Matsuo / ; Y Harada / ; T Hikosaka / ; T Nakagami / ; N Nakajima / ; Y Yamahara / ; K Ishibashi / ; R Sakai / ; K Akashi / ; M Katamura / ; T Yamamoto / ; N Kinoshita / ; H Irie / ; R Nakamura / ; M Nishio / ; T Sakamoto / ; H Hayashi / ; S Kimura / ; S Nishikawa / ; M Takeda / ; K Tateishi / ; A Matsumuro / ; Y Tsutsumi / ; T Takahashi / ; H Shiraishi / ; T Yamada /

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