| Predictors of early morbidity after major lung resection in patients with and without airflow limitation. | |
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MedLine Citation:
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PMID: 12400735 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The aim of the present study was to identify predictors of morbidity after major lung resection for non-small cell lung carcinoma in patients with forced expiratory volume in 1 second (FEV1) greater than or equal to 70% of predicted and in those with FEV1 less than 70% of predicted. METHODS: Five hundred forty-four patients who underwent lobectomy or pneumonectomy from 1993 through 2000 were retrospectively analyzed. The patients were divided into two groups: group A (450 cases), with FEV1 greater than or equal to 70%, and group B (94 cases), with FEV1 less than 70%. Differences between complicated and uncomplicated patients were tested within each group. RESULTS: Morbidity rate was not significantly different between group A and group B (20.4% and 24.5%, respectively; p = 0.4). In group A, multivariate analysis showed that predicted postoperative FEV1 was the only significant independent predictor of complications. In group B, no significant predictor was identified. CONCLUSIONS: In patients with preoperative FEV1 less than 70% of predicted, predicted postoperative FEV1 was not predictive of postoperative morbidity. Thus, predicted postoperative FEV1 should not be used alone as a selection criteria for operation in these high-risk patients. |
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Authors:
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Alessandro Brunelli; Majed Al Refai; Marco Monteverde; Armando Sabbatini; Francesco Xiumé; Aroldo Fianchini |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 74 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2002 Oct |
Date Detail:
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Created Date: 2002-10-28 Completed Date: 2002-11-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: United States |
Other Details:
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Languages: eng Pagination: 999-1003 Citation Subset: AIM; IM |
Affiliation:
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Department of Thoracic Surgery, University of Ancona, Italy. alexit_2000@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Non-Small-Cell Lung
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physiopathology,
surgery* Female Forced Expiratory Volume* Humans Lung Neoplasms / physiopathology, surgery* Male Pneumonectomy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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