Document Detail

Predictors of cognitive impairment severity in rural patients at a memory clinic.
MedLine Citation:
PMID:  23041397     Owner:  NLM     Status:  In-Data-Review    
Objective: Patients with dementia benefit from early assessment and diagnosis. In an attempt to identify factors leading to delay in referral, we investigated socio-demographic, clinical, and functional predictors of greater severity of cognitive impairment in dementia patients presenting to a memory clinic in Saskatoon, Saskatchewan. Methods: Data collection began in 2004 at the Rural and Remote Memory Clinic in Saskatoon, where non-institutionalized patients were referred by their family physicians. The patient and caregiver questionnaires and assessments administered at the clinic day appointment provided the socio-demographic, clinical, and functional patient variables, as well as the caregiver stress and burden variables. The dependent variable was patient cognitive impairment, as measured by Modified Mini-Mental State Examination (3MS) scores. Variables underwent univariate linear regression with 3MS scores in order to determine possible associations. A multiple regression analysis was conducted to determine predictors of cognitive impairment severity at clinic presentation. Results: Our sample included 198 patients (62% female). The mean age was 73.9 years (SD=9.2). We found that an age and gender interaction, years of formal education, Functional Activities Questionnaire score, and Brief Symptom Inventory score were significantly associated with 3MS scores (p<0.05). Conclusions: Increased cognitive impairment at presentation was predicted by fewer years of formal education, poorer functional ability, and less caregiver psychological distress. There was a significant interaction between age and gender: younger females were more cognitively impaired than younger males at clinic day, while in older patients, males were more cognitively impaired than females.
Catherine Lacny; Andrew Kirk; Debra G Morgan; Chandima Karunanayake
Related Documents :
23705847 - Neurological characterization of mice deficient in gsk3α highlight pleiotropic physiol...
958847 - Spatial constraints on focused attention: beyond the right-side advantage.
24787917 - Alzheimer's disease and methanol toxicity (part 2): lessons from four rhesus macaques (...
22985107 - Tackling indifference-clowning, dementia, and the articulation of a sensitive body.
23705847 - Neurological characterization of mice deficient in gsk3α highlight pleiotropic physiol...
20220027 - Visual influences on alignment to voice onset time.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques     Volume:  39     ISSN:  0317-1671     ISO Abbreviation:  Can J Neurol Sci     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0415227     Medline TA:  Can J Neurol Sci     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  774-81     Citation Subset:  IM    
College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vasospasm post pituitary surgery: systematic review and 3 case presentations.
Next Document:  Diagnostic challenges revealed from a neuropsychiatry movement disorders clinic.