| Predictors of adherence to treatment for latent tuberculosis infection in high-risk Latino adolescents: a behavioral epidemiological analysis. | |
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MedLine Citation:
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PMID: 12639595 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objective was to test whether theoretical variables predict adherence to treatment for latent tuberculosis infection in high-risk Latino adolescents. 286 Latino adolescents, age 13-18 years, were recruited from 10 middle/high schools in San Diego County, San Diego, USA. Participants completed a baseline interview and up to 9 monthly interviews. The cumulative number of pills consumed in 9 months was regressed on 16 independent variables, entered hierarchically in seven blocks. The final model accounted for 25% of the variance in adherence to isoniazid (INH), F (16, 230)=4.69, p<0.001. Adherence counseling (+), age (-), grades (+), being bicultural (+), and risk behaviors (-) were significantly related to adherence. Learning theories presume that adherence to medical regimens requires social support and freedom from physical and social barriers. Results support these theories. Future studies should explore additional precepts in order to identify additional predictors and to maximize adherence to INH among Latino adolescents and other high-risk populations. Doing so should decrease the risk of active TB among high-risk racial/ethnic and foreign-born populations. |
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Authors:
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Melbourne Hovell; Elaine Blumberg; Laura Gil-Trejo; Alicia Vera; Norma Kelley; Carol Sipan; C Richard Hofstetter; Sandra Marshall; Jill Berg; Lawrence Friedman; Antonino Catanzaro; Kathleen Moser |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Social science & medicine (1982) Volume: 56 ISSN: 0277-9536 ISO Abbreviation: Soc Sci Med Publication Date: 2003 Apr |
Date Detail:
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Created Date: 2003-03-17 Completed Date: 2003-06-16 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8303205 Medline TA: Soc Sci Med Country: England |
Other Details:
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Languages: eng Pagination: 1789-96 Citation Subset: IM |
Affiliation:
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Center for Behavioral Epidemiology, Graduate School of Public Health, San Diego State University, 9245 Sky Park Court, Ste 230, 92123, CA, USA. mhovell@projects.sdsu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acculturation Adolescent Adolescent Behavior / ethnology* Antitubercular Agents / administration & dosage* California Counseling Female Hispanic Americans / psychology* Humans Isoniazid / administration & dosage* Male Mycobacterium tuberculosis / pathogenicity Patient Compliance / ethnology* Premedication Risk-Taking Self Efficacy Tuberculosis / drug therapy, ethnology, microbiology, prevention & control* |
| Grant Support | |
ID/Acronym/Agency:
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1RO1HL5S73801/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antitubercular Agents; 54-85-3/Isoniazid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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