| Predictors of poor weight gain in infants with a single ventricle. | |
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MedLine Citation:
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PMID: 20472248 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess growth from the time of neonatal discharge to the time of performance of the bidirectional Glenn (BDG) procedure in infants with a single ventricle and determine predictors of poor growth. STUDY DESIGN: We performed a retrospective case series of infants who underwent the BDG procedure at our institution between January 2001 and December 2007 (n=102). Anthropometric and clinical data were recorded during neonatal hospitalization and before BDG. Outcome variables included weight-for-age z-score (WAZ) at the time of BDG and average daily weight gain between neonatal discharge and BDG. RESULTS: Median age at the time of BDG was 5.1 months (range, 2.4-10 months), and median WAZ was -0.4 (range, -2.6 to 3.2) at neonatal admission and -1.3 (range, -3.9 to 0.6) at the time of BDG. Non-Caucasian infants (P=.03) and those with lower WAZ at neonatal discharge (P<.0001) had a lower WAZ at BDG. Being formula-fed at neonatal discharge (P=.04), and having higher mean pulmonary arterial pressure (P=.04) and systemic oxygen saturation (P=.006) were associated with lower average daily weight gain between neonatal discharge and BDG. CONCLUSIONS: Infants with a single ventricle have poor weight gain between neonatal discharge and BDG. Non-Caucasian infants and those with evidence of increased pulmonary blood flow are at particular risk for growth failure. |
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Authors:
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Jeffrey B Anderson; Robert H Beekman; Pirooz Eghtesady; Heidi J Kalkwarf; Karen Uzark; Jack E Kehl; Bradley S Marino |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-15 |
Journal Detail:
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Title: The Journal of pediatrics Volume: 157 ISSN: 1097-6833 ISO Abbreviation: J. Pediatr. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-23 Completed Date: 2010-09-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 407-13, 413.e1 Citation Subset: AIM; IM |
Copyright Information:
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Copyright (c) 2010 Mosby, Inc. All rights reserved. |
Affiliation:
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Division of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. jeffrey.anderson@cchmc.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Heart Defects, Congenital / physiopathology* Heart Ventricles / abnormalities* Humans Infant Male Prognosis Retrospective Studies Weight Gain* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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